Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Investigation of gastrointestinal injury-related biomarkers in dairy cattle with displaced abomasum
Veterinary Medicine and Science · Kasım 2023
YÖKSİS Kayıtları
Investigation of gastrointestinal injury‐related biomarkers in dairy cattle with displaced abomasum
Veterinary Medicine and Science · 2023 SCI
DOÇENT MERVE İDER →
Investigation of gastrointestinal injury-related biomarkers in
dairy cattle with displaced abomasum
Wiley · 2023 SCI
ARAŞTIRMA GÖREVLİSİ SÜLEYMAN SERHAT İYİGÜN →
Investigation of gastrointestinal injury‐related biomarkers in dairy cattle with displaced abomasum
Veterinary Medicine and Science · 2023 SCI-Expanded
PROFESÖR FAHRETTİN ALKAN →
Investigation of gastrointestinal injury‐related biomarkers in dairy cattle with displaced abomasum
Wiley · 2023 SCI-Expanded
PROFESÖR MAHMUT OK →
Investigation of gastrointestinal injury-related biomarkers in
dairy cattle with displaced abomasum
Wiley · 2023 SCI
PROFESÖR MAHMUT OK →
Makale Bilgileri
DergiVeterinary Medicine and Science
Yayın TarihiKasım 2023
Cilt / Sayfa9 · 2893-2900
Scopus ID2-s2.0-85173482857
Erişim🔓 Açık Erişim
Özet
Background: Displaced abomasum (DA) is one of the most important metabolic disorders of dairy cattle. In DA, ischaemic damage may occur as a result of impaired perfusion due to abomasal displacement, which may result in gastrointestinal mucosal damage. Objective: Investigation of gastrointestinal tissue damage in cattle with right displacement of the abomasum (RDA) and left displacement of the abomasum (LDA) using intestinal-related biomarkers. Methods: Forty-eight DA (24 LDA, 24 RDA) and 15 healthy Holstein dairy cows were enrolled between March 2021 and July 2022. Serum biomarkers including gamma-enteric smooth muscle actin (ACTG-2), liver-fatty acid binding proteins (L-FABP), platelet activating factor (PAF), trefoil factor-3 (TFF-3), leptin, claudin-3 and interleukin-8 (IL-8) concentrations were measured from venous blood samples. Results: L-FABP concentrations in the LDA group and TFF-3 concentrations in the RDA group were lower than in the control group. The leptin concentration of the RDA group was higher than that of the other groups. There was a negative correlation between lactate, leptin and IL-8 concentrations. There was a negative correlation between lactate and TFF-3, whereas leptin and lactate were positively correlated. Leptin was the more reliable biomarker for discriminating between RDA and LDA cases. Conclusion: Changes in serum L-FABP, TFF-3 and leptin concentrations in cattle with DA may reflect acute intestinal injury and the subsequent repair phase. However, these biomarkers had poor diagnostic performance in discriminating between healthy and cattle with DA, while leptin emerged as the most useful marker in differentiating LDA from RDA cases.
Yazarlar (9)
1
Merve Ider
ORCID: 0000-0003-2928-5452
2
Ramazan Yildiz
3
Amir Naseri
4
Erdem Gülersoy
ORCID: 0000-0001-8511-0150
5
Fahrettin Alkan
6
M. Ok
7
Alper Erturk
8
Kadir Sulu
ORCID: 0000-0002-7246-8185
9
Murat Kaan Durgut
Anahtar Kelimeler
cattle
left displacement of abomasum
leptin
liver-fatty acid binding proteins
right displacement of abomasum
trefoil factor-3
Kurumlar
Burdur Mehmet Akif Ersoy Üniversitesi
Burdur Turkey
Harran Üniversitesi
Sanliurfa Turkey
Mustafa Kemal Üniversitesi
Antakya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Siirt Üniversitesi
Siirt Turkey
Metrikler
1
Atıf
9
Yazar
6
Anahtar Kelime