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The evaluation of coagulation profiles in calves with suspected septic shock

Veterinary Research Communications · Temmuz 2006

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YÖKSİS Kayıtları
The Evaluation of Coagulation Profiles in Calves with Suspected Septic Shock
Veterinary Research Communications · 2006 SSCI 23 atıf
PROFESÖR RAMAZAN ÇÖL →
The Evaluation of Coagulation Profiles in Calves with Suspected Septic Shock
Veterinary Research Communications · 2006 SSCI 15 atıf
PROFESÖR HASAN GÜZELBEKTEŞ →

Makale Bilgileri

DergiVeterinary Research Communications
Yayın TarihiTemmuz 2006
Cilt / Sayfa30 · 497-503
Özet The purpose of the study reported here was to evaluate the haemostatic function in calves with suspected septic shock and to reflect the occurrence of disseminated intravascular coagulation (DIC). Twenty-six calves suspected of having septic shock (experimental group) and 10 clinically healthy calves (control group) were used. On admission, the experimental group of calves had been ill for an average of 2 days. Therapy was applied to the experimental group of calves. The packed cell volume (PCV), haemoglobin (Hb), white blood cell (WBC), red blood cell (RBC) and platelet (PLT) counts were determined. Blood smears for toxic neutrophil and schistocyte intensity were evaluated. For the coagulation profile, plasma activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT), fibrinogen and fibrin/fibrinogen degradation products (FDPs) values were determined. Toxic neutrophils in blood smears were observed in 12 calves of the experimental group. APTT was prolonged in the experimental group compared with the control group (p < 0.05). Fibrinogen concentration was found to be higher in the experimental group than in the control group (p < 0.001). Total leukocyte counts were higher in the experimental group compared with the control group (p < 0.01). Platelet counts in the experimental group were lower than the control group (p < 0.001). However, when the individual values of coagulation profiles of each calf were evaluated, 8 calves had at least three abnormal coagulation profiles (APTT > 72s, PT > 34.5s, TT > 33.7s, FDPs > 5 μg/ml, PLT ≤ 150 × 103/mm3) and abnormal erythrocyte morphology (schistocytes ≥ 1). The most common abnormal tests in the coagulation profile were APTT and PT (7 cases), FDPs (6 cases), thrombocytopenia (4 cases), and schistocytes in blood smears (8 cases) in these 8 calves. The results of this study indicate that DIC might be a significant risk factor for mortality in calves with suspected septic shock. © Springer Science + Business Media, Inc. 2006.

Yazarlar (8)

1
K. Irmak
2
Ismail Sen
3
Ramazan Col
4
F. M. Birdane
5
Hasan Guzelbektes
ORCID: 0000-0002-0227-0691
6
T. Civelek
7
A. Yilmaz
8
Kursad Turgut

Anahtar Kelimeler

Calves DIC Septic shock

Kurumlar

Afyon Kocatepe Üniversitesi
Afyonkarahisar Turkey
Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

37
Atıf
8
Yazar
3
Anahtar Kelime

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