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Echocardiographic assessment of left ventricular systolic function in neonatal calves with naturally occurring sepsis or septic shock due to diarrhea

Research in Veterinary Science · Ekim 2019

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YÖKSİS Kayıtları
Echocardiographic assessment of left ventricular systolic function in neonatal calves with naturally occurring sepsis or septic shock due to diarrhea
Research in Veterinary Science · 2019 SCI-Expanded
PROFESÖR HASAN GÜZELBEKTEŞ →
Echocardiographic assessment of left ventricular systolic function in neonatal calves with naturally occurring sepsis or septic shock due to diarrhea
Research in Veterinary Science · 2019 SCI-Expanded
DOÇENT AMİR NASERİ →

Makale Bilgileri

DergiResearch in Veterinary Science
Yayın TarihiEkim 2019
Cilt / Sayfa126 · 103-112
Özet Sepsis is associated with clinically relevant cardiovascular changes. The objectives of this study were to evaluate the clinical value of echocardiography for monitoring left ventricular (LV) systolic function in septic calves. A prospective longitudinal study was performed using a convenience sample. Twenty septic calves and 10 healthy calves were enrolled in the study. Arterial blood pressure (BP) was measured and M-mode echocardiography performed to characterize LV systolic function; the latter included measurement of ejection fraction, EF; stroke volume, SVI and cardiac output indexed to body weight, CI; E-point of septal separation, EPSS; pre-ejection period, PEP; ejection time, LVET; ratio of PEP to LVET; velocity of circumferential shortening, Vcf, LV end-diastolic volume index (LVEDVI) and LV end-systolic volume index (LVESVI) on admission and 6, 24, 48 and 72 h later in septic calves and once in healthy calves. Admission data were compared using the Mann-Whitney U test and P <.05 was considered significant. Decreased preload and afterload were present in septic calves, as indicated by marked decreases in BP, LVEDVI, LVESVI, SVI, CI, EPSS when compared to healthy calves. Systolic function appeared adequate in septic calves, based on EF and FS compared to control calves. There was no difference in heart rate, LVET, PEP:LVET, or Vcf between septic and health calves. We conclude that circulatory dysfunction, rather than systolic dysfunction predominates in septic calves. Positive associations on admission between CI and LVEDVI, LVESVI, and SVI support this conclusion. Echocardiographic determination of LVEDVI and CI appears useful in directing treatment in septic calves.

Yazarlar (5)

1
Amir Naseri
2
Ismail Sen
3
Kursad Turgut
4
Hasan Guzelbektes
ORCID: 0000-0002-0227-0691
5
Peter D. Constable

Anahtar Kelimeler

Contractility Ejection fraction Hypotension Systemic inflammatory response syndrome

Kurumlar

Kyrgyz-Turkish Manas University
Bishkek Kyrgyzstan
Selçuk Üniversitesi
Selçuklu Turkey
University of Illinois Urbana-Champaign
Urbana United States
Yakın Doğu Üniversitesi
Nicosia Cyprus

Metrikler

13
Atıf
5
Yazar
4
Anahtar Kelime

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