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Scopus 🔓 Açık Erişim YÖKSİS DOI Eşleşti SJR Q2

Serum biochemistry of lumpy skin disease virus-infected cattle

Biomed Research International · Ocak 2016

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YÖKSİS Kayıtları
Serum Biochemistry of Lumpy Skin Disease Virus Infected Cattle
BioMed Research International · 2016 SCI-Expanded
Prof. Dr. OĞUZHAN AVCI →
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Makale Bilgileri

ISSN23146133
Yayın TarihiOcak 2016
Cilt / Sayfa2016
Erişim🔓 Açık Erişim
Özet Lumpy skin disease is an economically important poxvirus disease of cattle. Vaccination is the main method of control but sporadic outbreaks have been reported in Turkey. This study was carried out to determine the changes in serum biochemical values of cattle naturally infected with lumpy skin disease virus (LSDV). For this study, blood samples in EDTA, serum samples, and nodular skin lesions were obtained from clinically infected animals (n = 15) whereas blood samples in EDTA and serum samples were collected from healthy animals (n = 15). A quantitative real-time PCR method was used to detect Capripoxvirus (CaPV) DNA in clinical samples. A real-time PCR high-resolution melt assay was performed to genotype CaPVs. Serum cardiac, hepatic, and renal damage markers and lipid metabolism products were measured by autoanalyzer. LSDV nucleic acid was detected in all samples which were obtained from clinically infected cattle. The results of serum biochemical analysis showed that aspartate aminotransferase, alkaline phosphatase, total protein, and creatinine concentrations were markedly increased in serum from infected animals. However, there were no significant differences in the other biochemical parameters evaluated. The results of the current study suggest that liver and kidney failures occur during LSDV infection. These findings may help in developing effective treatment strategies in LSDV infection.

Yazarlar (4)

1
Murat Sevik
2
Oğuzhan Avci
ORCID: 0000-0001-9299-4695
3
Müge Dogan
4
Ömer Bariş Ince

Kurumlar

Agriculture and Rural Development Support Institution
Burdur Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Veterinary Control Institute
Meram Turkey
Scimago Dergi (ISSN Eşleşmesi)
BioMed Research International
Q2 OA
SJR Skoru0,748
H-Index219
YayıncıJohn Wiley and Sons Ltd
ÜlkeUnited Kingdom
Biochemistry, Genetics and Molecular Biology (miscellaneous) (Q2)
Immunology and Microbiology (miscellaneous) (Q2)
Medicine (miscellaneous) (Q2)
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51
Atıf
4
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