Scopus
YÖKSİS Eşleşti
Element profiles in blood and teeth samples of children with congenital heart diseases in comparison with healthy ones
Journal of Trace Elements in Medicine and Biology · Ocak 2021
YÖKSİS Kayıtları
Element profiles in blood and teeth samples of children with congenital heart diseases in comparison with healthy ones
Journal of Trace Elements in Medicine and Biology · 2021 SCI-Expanded
PROFESÖR SUZAN YALÇIN →
Makale Bilgileri
DergiJournal of Trace Elements in Medicine and Biology
Yayın TarihiOcak 2021
Cilt / Sayfa63
Scopus ID2-s2.0-85094108378
Özet
Background: Some elements were claimed to play a role in the pathogenesis of congenital heart defects (CHD) and influence the general well-being and health of these children. Objectives: We aimed to assess the levels of some elements simultaneously in the blood and teeth samples of children with cyanotic and acyanotic CHD compared with healthy children. Methods: A total of 39 children with CHD (11 with cyanotic and 28 with acyanotic CHD) and 42 age- and sex-adjusted controls were enrolled. Levels of 13 elements, including magnesium, phosphorus, calcium, chromium, manganese, iron, copper, zinc, strontium, cadmium, lead, mercury, and molybdenum, were assessed using inductively coupled plasma mass spectrometry. Results: Children with cyanotic and acyanotic CHD had significantly lower teeth calcium and calcium/phosphorus ratio as compared to the controls after adjusting for confounders. The mean blood iron level was found to be significantly higher in the cyanotic CHD group compared to the other groups. In addition, children with acyanotic CHD had significantly higher teeth copper levels, higher blood molybdenum and lower blood magnesium levels compared to the healthy control group. Blood cadmium and mercury levels were found to be significantly elevated in both the cyanotic and acyanotic CHD groups compared to the healthy control group. There were no differences in toxic metal levels of teeth in cases with CHD. Conclusion: Monitoring adequate and balanced gestational micronutrient intake might support not only maternal health but also fetal cardiac development and infant well-being. Supplementation of magnesium should be evaluated in patients having CHD.
Yazarlar (4)
1
Siddika Songül YALÇIN
ORCID: 0000-0001-9061-4281
2
Yasemin Nuran Donmez
3
Ebru Aypar
4
S. YALÇiN
Anahtar Kelimeler
Blood
Congenital heart defects
Elements
Teeth
Kurumlar
Hacettepe Üniversitesi
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
13
Atıf
4
Yazar
4
Anahtar Kelime