Scopus
YÖKSİS DOI Eşleşti
SJR Q1
Single dose of tiotropium improves the 6-minute walk distance in chronic obstructive pulmonary disease
Lung · Ağustos 2006
YÖKSİS Kayıtları
Single Dose of Tiotropium Improves the 6 Minute Walk Distance in Chronic Obstructive Pulmonary Disease
Lung · 2006 SSCI 12 atıf
Prof. Dr. NİLSEL OKUDAN →
YÖKSİS Kayıtları — ISSN Eşleşmesi
The relationship between HRCT and pulmonary function in Behcet s disease
2004 ISSN: 0341-2040 SSCI 7 atıf
Prof. Dr. NİLSEL OKUDAN →
Single Dose of Tiotropium Improves the 6 Minute Walk Distance in Chronic Obstructive Pulmonary Disease
2006 ISSN: 0341-2040 SSCI 12 atıf
Prof. Dr. NİLSEL OKUDAN →
Makale Bilgileri
Dergi
Lung
ISSN03412040
Yayın TarihiAğustos 2006
Cilt / Sayfa184 · 201-204
Scopus ID2-s2.0-33749184497
Özet
The aim of this study was to evaluate the effect of a single dose of tiotropium on the exercise capacity of stable chronic obstructive pulmonary disease (COPD) patients. The study was a randomized, placebo-controlled, double-blind, cross-over study. Forty-four stable COPD patients with moderate to severe airway obstruction were selected according to the GOLD criteria. The regular anticholinergic therapies of the patients were interrupted one week before the test. In the morning hours of the first day, half the group was given one capsule (18 mcg) of tiotropium and the other half was given placebo as inhalation using the HandiHaler® device. Before and 120 min after the medication, the 6-min walk test was performed. Oxygen saturation, modified Borg dyspnea ratings, blood pressure, and heart rate were recorded before and after the test. The same procedure was repeated at the same time on the third day but this time the patients were given placebo if they used tiotropium on the first day and vice versa. Before using tiotropium or placebo there was no difference between 6-min walk distances. The 6-min walk distance after the use of tiotropium (429.3 ± 70.6 m) was significantly longer than that after the use of placebo (414.7 ± 74.6 m). The changes in Borg dyspnea ratings and arterial oxygen saturation values with tiotropium and placebo use were not significant. We conclude that exercise capacity might be improved by using a single-dose tiotropium inhalation in moderate to severe COPD patients. © 2006 Springer Science+Business Media, Inc.
Yazarlar (4)
1
Nilsel Okudan
2
Mehmet Gök
3
H. Gökbel
4
Mecit Suerdem
Anahtar Kelimeler
Chronic obstructive pulmonary disease
Exercise testing
Exercise tolerance
Tiotropium
Walking test
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Lung
Q1
SJR Skoru1,034
H-Index78
YayıncıSpringer
ÜlkeUnited States
Pulmonary and Respiratory Medicine (Q1)
Metrikler
17
Atıf
4
Yazar
5
Anahtar Kelime