Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Effects of CoQ10 supplementation and swimming training on exhaustive exercise-induced oxidative stress in rat heart
Bratislava Medical Journal · Aralık 2012
YÖKSİS Kayıtları
Effects of CoQ10 supplementation and swimming training on exhaustiveexercise induced oxidative stress in rat heart
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY · 2012 SSCI 2 atıf
PROFESÖR NİLSEL OKUDAN →
Effects of CoQ10 supplementation and swimming training on exhaustive exercise induced oxidative stress in rat heart
Bratislava Medical Journal · 2012 SCI-Expanded
PROFESÖR MUAZ BELVİRANLI →
Makale Bilgileri
DergiBratislava Medical Journal
Yayın TarihiAralık 2012
Cilt / Sayfa113 · 393-399
Scopus ID2-s2.0-84871751627
Erişim🔓 Açık Erişim
Özet
This study examined the combined effects of swimming training and coenzyme Q10 (CoQ10) supplementation on exhaustive exercise-induced oxidative stress in rat heart. The study was carried out with 4-monthold young adult male Wistar rats. Sixty four rats were divided mainly into two groups: trained and control. Each group was further divided into four subgroups: rest, exhausted, rest with CoQ10, exhausted with CoQ10. The training program consisted of swimming one hour each day, fi ve days a week, for six weeks. At the end of sixth week, rats in exhausted exercise group were forced to swim until exhaustion and then they were immediately sacrifi ced, while rats in rest group were sacrifi ced at rest. Training alone or in combination with CoQ10 supplementation reduced to increasing MDA levels due to exhaustive exercise in rat heart (p<0.05). The trained-rest with CoQ10 group showed lower 8-OHdG levels than the control-rest with CoQ10 group. Exhaustive exercise effect was signifi cant on SOD activity. Exhaustive exercise increased GSH levels in control groups while decreased GSH levels in training groups (p<0.05). In conclusion, the results suggest that CoQ10 supplementation combined with training may inhibit lipid peroxidation and DNA damage in the heart tissue. Also, it can be said that SOD activity and GSH levels were not infl uenced by CoQ10 supplementation.
Yazarlar (6)
1
Nilsel Okudan
2
Serkan Revan
3
Şükrü Serdar Balci
4
M. Belvirali
5
Hamdi Pepe
6
H. Gökbel
Anahtar Kelimeler
CoQ 10
Oxidative stress
Swimming training
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
13
Atıf
6
Yazar
3
Anahtar Kelime