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Protective effects of curcumin supplementation on intestinal ischemia reperfusion injury

Phytomedicine · Temmuz 2013

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YÖKSİS Kayıtları
Protective effects of curcumin supplementation on intestinal ischemiareperfusion injury
PHYTOMEDICINE · 2013 SSCI 7 atıf
PROFESÖR NİLSEL OKUDAN →
Protective effects of curcumin supplementation on intestinal ischemia reperfusion injury
Phytomedicine · 2013 SSCI
PROFESÖR MUAZ BELVİRANLI →

Makale Bilgileri

DergiPhytomedicine
Yayın TarihiTemmuz 2013
Cilt / Sayfa20 · 844-848
Özet The aim of this study was to investigate the effects curcumin on inflammation and oxidative stress markers in the intestinal ischemia reperfusion (IIR) injury induced rats. Rats were divided into four groups: sham (S), intestinal IR (IIR), curcumin plus sham (CS), and curcumin plus intestinal IR (CIIR). Curcumin was given 200 mg kg-1 for 20 days. IIR was produced by 45 min of intestinal ischemia followed by a 120 min of reperfusion. Although interleukin-6 levels tended to increase in IIR group tumor necrosis factor-α levels were not different. Intestinal myeloperoxidase activity in CS group was lower than IIR group. In intestine and heart tissues, malondialdehyde levels in CS and CIIR groups were lower than S and IIR groups. Superoxide dismutase activity in CIIR group was higher than IIR group in intestine and lung tissues. Curcumin has a protective role against ischemia reperfusion injury. © 2013 Elsevier GmbH.

Yazarlar (5)

1
Nilsel Okudan
2
Muaz Belviranli
3
H. Gökbel
4
Mehmet Öz
5
A. Kumak

Anahtar Kelimeler

Curcumin Heart Intestinal ischemia reperfusion Lung Oxidative stress

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

34
Atıf
5
Yazar
5
Anahtar Kelime

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