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Lack of association between leptin levels and leptin gene polymorphism in obese women

Archives of Physiology and Biochemistry · Ekim 2014

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YÖKSİS Kayıtları
Lack of association between leptin levels and leptin gene polymorphism in obese women
Archives of Physiology and Biochemistry · 2014 SCI-Expanded
PROFESÖR MUAZ BELVİRANLI →
Lack of association between leptin levels and leptin gene polymorphism in obese women
Archives of Physiology and Biochemistry · 2014 SCI-Expanded
PROFESÖR NİLSEL OKUDAN →
Lack of association between leptin levels and leptin gene polymorphism in obese women
Archives of Physiology and Biochemistry · 2014 SCI-Expanded
PROFESÖR HASAN ACAR →
Lack of association between leptin levels and leptin gene polymorphism in obese women
Archives of Physiology and Biochemistry · 2015 SSCI
PROFESÖR HASAN ACAR →

Makale Bilgileri

DergiArchives of Physiology and Biochemistry
Yayın TarihiEkim 2014
Cilt / Sayfa120 · 136-139
DOI10.3109/13813455.2014.946933
Scopus ID2-s2.0-84907484685
Özet The aim of the present study was to evaluate the relationship between oligopolymorphism in the 25th codon of leptin gene and obesity. Eighty-seven obese women and 75 healthy women were constituted obese and control groups. Body fat percent, fat mass and lean body mass were determined by bioimpedance meter and leptin levels were determined. The presence of 25th codon oligopolymorphism in the leptin gene was done by PCR-RFLP technique. Mean leptin levels were 38.5±22.0ng/ml, and 147.9±44.8ng/ml in the control and obese groups, respectively. The correlations of serum leptin level to body fat percentage and fat mass in the control group were significant. The correlations in the obese group were not significant. This data implies that the difference of leptin levels between control and obese groups are more likely to be associated with alterations in the leptin gene other than 25th codon or alterations in the leptin receptor gene.

Yazarlar (5)

1
Nilsel Okudan
2
H. Gökbel
3
Hasan Acar
4
Selim Uzunoʇlu
5
Muaz Belviranli

Anahtar Kelimeler

Leptin gene Obesity Polymorphism

Kurumlar

Manisa Celâl Bayar Üniversitesi
Manisa Turkey
Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

3
Atıf
5
Yazar
3
Anahtar Kelime

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NO
NİLSEL OKUDAN
PROFESÖR

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