Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q3
Effects of grape seed extract on oxidative stress and antioxidant defense markers in streptozotocin-induced diabetic rats
Turkish Journal of Medical Sciences · Ocak 2015
YÖKSİS Kayıtları
Effects of grape seed extract on oxidative stress and antioxidant defensemarkers in streptozotocin induced diabetic rats
TURKISH JOURNAL OF MEDICAL SCIENCES · 2015 SCI-Expanded
Prof. Dr. NİLSEL OKUDAN →
Effects of grape seed extract on oxidative stress and antioxidant defensemarkers in streptozotocin induced diabetic rats
TURKISH JOURNAL OF MEDICAL SCIENCES · 2015 SCI-Expanded
Prof. Dr. MUAZ BELVİRANLI →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Evaluation of 48 week response of treatment naive chronic hepatitis B patients to 0 5 mg day entecavir
2014 ISSN: 1300-0144 SCI-Expanded
Prof. Dr. ŞUA SÜMER →
Serum Interleukin 8 Levels May Predict Relapse In Brucellosis
2012 ISSN: 1300-0144 SCI-Expanded
Prof. Dr. NAZLIM AKTUĞ DEMİR →
Evaluation of 48 week Response of Treatment Naive Chronic Hepatitis B Patients to 0 5 mg day Entecavir
2014 ISSN: 1300-0144 SCI-Expanded
Prof. Dr. NAZLIM AKTUĞ DEMİR →
Pregnancy associated plasma protein A and procalcitonin as markers of myocardial injury in patients with acute coronary syndrome
2015 ISSN: 13000144 SCI-Expanded
Prof. Dr. BAHADIR ÖZTÜRK →
The efficacy of intermittant low dose systemic corticosteroid in the treatment of alopecia areata
2004 ISSN: 1300-0144 SCI-Expanded 1 atıf
Prof. Dr. GÜLCAN SAYLAM KURTİPEK →
Pregnancy associated plasma protein A and procalcitonin as markers of myocardial injury in patients with acute coronary syndrome
2015 ISSN: 13000144 SCI-Expanded
Prof. Dr. HASAN KARA →
Analysis of periprocedural medical complications during carotid angioplasty and stent placement
2010 ISSN: 1300-0144 SCI-Expanded
Prof. Dr. İBRAHİM ÖZKAN ÖNAL →
High risk febrile neutropenia and its management in childrenwith solid tumors and lymphoma
2015 ISSN: 13000144 SCI-Expanded
Prof. Dr. YAVUZ KÖKSAL →
Effects of grape seed extract on oxidative stress and antioxidant defensemarkers in streptozotocin induced diabetic rats
2015 ISSN: 13000144 SCI-Expanded
Prof. Dr. MUAZ BELVİRANLI →
Effectiveness of pelvic floor muscle training on symptoms and uroflowmetryparameters in female patients with overactive bladder
2015 ISSN: 13000144 SCI-Expanded
Prof. Dr. EVRİM ÇAKMAKÇI →
Effects of grape seed extract on oxidative stress and antioxidant defensemarkers in streptozotocin induced diabetic rats
2015 ISSN: 13000144 SCI-Expanded
Prof. Dr. NİLSEL OKUDAN →
Pregnancy associated plasma protein A and procalcitonin as markers of myocardial injury in patients with acute coronary syndrome
2015 ISSN: 13000144 SCI-Expanded
Prof. Dr. ABDULLAH SİVRİKAYA →
Refeeding hypophosphatemia a potentially fatal danger in the intensive care unit
2014 ISSN: 13000144 SCI-Expanded
Prof. Dr. SÜLEYMAN BALDANE →
Comparison of the efficacy of prednisolone montelukast and omalizumab in an experimental allergic rhinitis model
2014 ISSN: 1300-0144 SCI-Expanded
Prof. Dr. BANU BOZKURT →
Pregnancy associated plasma protein A and procalcitonin as markers of myocardial injury in patients with acute coronary syndrome
2015 ISSN: 13000144 SCI-Expanded
Prof. Dr. AYŞEGÜL BAYIR →
Comparison of the efficacy of prednisolone montelukast and omalizumab in an experimental allergic rhinitis model
2014 ISSN: 13000144 SCI-Expanded
Prof. Dr. METE KAAN BOZKURT →
Hypo and hypervolemic edema in children with steroid sensitive nephrotic syndrome
2015 ISSN: 13000144 SCI-Expanded Q3
Dr. Öğr. Üyesi MEHMET AKİF BÜYÜKAVCI →
Evaluation of dental technician’s pneumoconiosis using chest X-rayand HRCT: correlation between radiological and functional findings
2017 ISSN: 13000144 SCI-Expanded
Prof. Dr. RECAİ ERGÜN →
Cytokeratin 18 and h FABP levels in intestinal ischemia reperfusioninjury role of coenzyme Q10
2013 ISSN: 1300-0144 SSCI 2 atıf
Prof. Dr. NİLSEL OKUDAN →
N terminal pro brain natriuretic peptide levels in children with allergic rhinitis
2016 ISSN: 1300-0144 SCI-Expanded
Prof. Dr. HÜSAMETTİN VATANSEV →
Makale Bilgileri
ISSN13000144
Yayın TarihiOcak 2015
Cilt / Sayfa45 · 489-495
Scopus ID2-s2.0-84929725029
Erişim🔓 Açık Erişim
Özet
Background/aim: To evaluate the effects of grape seed extract (GSE) supplementation on oxidative stress and antioxidant markers in streptozotocin (STZ)-induced diabetic rats. Materials and methods: Tirty-six male rats were divided into the following four groups: control, GSE-supplemented control, diabetic, and GSE-supplemented diabetic. Beginning on day 7 afer STZ injection, the rats were administered GSE (100 mg kg<sup>–1</sup> day<sup>–1</sup>) in drinking water for 6 weeks. At the end of week 6, rats were sacrifced by cardiac puncture. Plasma nitric oxide (NO) levels and xanthine oxidase (XO), adenosine deaminase (ADA), and glutathione peroxidase (GPx) activities were analyzed. Results: Both XO and ADA activities increased and NO levels decreased in diabetic rats (P < 0.05). GSE supplementation normalized all of these changes. Antioxidant enzyme activities decreased in diabetic rats compared to the controls (P < 0.05). GSE supplementation increased antioxidant enzyme activities in both diabetic and healthy rats (P < 0.05). Conclusion: Tese fndings suggest that 6 weeks of oral GSE supplementation may prevent oxidative stress and improve antioxidant status in diabetic rats.
Yazarlar (4)
1
Muaz Belviranli
2
H. Gökbel
3
Nilsel Okudan
4
Sadik Büyükbaş
Anahtar Kelimeler
Adenosine deaminase
Antioxidant enzyme activity
Experimental diabetes
Grape seed extract
Nitric oxide
Oxidative stress
Kurumlar
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Turkish Journal of Medical Sciences
Q3
SJR Skoru0,386
H-Index44
YayıncıTUBITAK
ÜlkeTurkey
Medicine (miscellaneous) (Q3)
Metrikler
13
Atıf
4
Yazar
6
Anahtar Kelime