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Repeated supramaximal exercise-induced oxidative stress: Effect of β-Alanine plus creatine supplementation

Asian Journal of Sports Medicine · Mart 2016

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YÖKSİS Kayıtları
Repeated Supramaximal Exercise Induced Oxidative Stress Effect of Alanine Plus Creatine Supplementation
Asian Journal of Sports Medicine · 2016 SCOPUS
PROFESÖR NİLSEL OKUDAN →
Repeated Supramaximal Exercise Induced Oxidative Stress Effect of Alanine Plus Creatine Supplementation
Asian Journal of Sports Medicine · 2016 IM: Index Medicus
PROFESÖR ŞÜKRÜ SERDAR BALCI →
Repeated Supramaximal Exercise Induced Oxidative Stress Effect of Alanine Plus Creatine Supplementation
Asian Journal of Sports Medicine · 2016 SCOPUS
PROFESÖR MUAZ BELVİRANLI →

Makale Bilgileri

DergiAsian Journal of Sports Medicine
Yayın TarihiMart 2016
Cilt / Sayfa7
Özet Background: Carnosine is a dipeptide formed from the β-alanine and histidine amino acids and found in mainly in the brain and muscle, especially fast twitch muscle. Carnosine and creatine has an antioxidant effect and carnosine accounts for about 10% of the muscle's ability to buffer the H+ ions produced by exercise. Objectives: The aim of the study was to investigate the effects of beta alanine and/or creatine supplementation on oxidant and antioxidant status during repeated Wingate tests (WTs). Patients and Methods: Forty four sedentary males participated in the study. Participants performed three 30s WTs with 2 minutes rest between exercise bouts. After the first exercise session, the subjects were assigned to one of four groups: Placebo, Creatine, Beta-alanine and Beta-alanine plus creatine. Participants ingested twice per day for 22 consecutive days, then four times per day for the following 6 days. After the supplementation period the second exercise session was applied. Blood samples were taken before and immediately after the each exercise session for the analysis of oxidative stress and antioxidant markers. Results: Malondialdehyde levels and superoxide dismutase activities were affected by neither supplementation nor exercise. During the pre-supplementation session, protein carbonyl reduced and oxidized glutathione (GSH and GSSG) levels increased immediately after the exercise. However, during the post-supplementation session GSH and GSSG levels increased in beta-alanine and beta-alanine plus creatine groups immediately after the exercise compared to pre-exercise. In addition, during the post-supplementation session total antioxidant capacity increased in beta-alanine group immediately after the exercise. Conclusions: Beta-alanine supplementation has limited antioxidant effect during the repeated WTs.

Yazarlar (5)

1
Muaz Belviranli
2
Nilsel Okudan
3
Serkan Revan
4
Serdar Balci
5
H. Gökbel

Anahtar Kelimeler

Antioxidant Beta-alanine Circuit-based exercise Creatine Oxidative stress

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

3
Atıf
5
Yazar
5
Anahtar Kelime

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