Scopus
YÖKSİS Eşleşti
Association of Circulating Irisin with Insulin Resistance and Oxidative Stress in Obese Women
Hormone and Metabolic Research · Eylül 2016
YÖKSİS Kayıtları
Association of Circulating Irisin with Insulin Resistance and Oxidative Stress in Obese Women
Hormone and Metabolic Research · 2016 SCI
PROFESÖR NİLSEL OKUDAN →
Association of Circulating Irisin with Insulin Resistance and Oxidative Stress in Obese Women
Hormone and Metabolic Research · 2016 SCI
PROFESÖR MUAZ BELVİRANLI →
Makale Bilgileri
DergiHormone and Metabolic Research
Yayın TarihiEylül 2016
Cilt / Sayfa48 · 653-657
Scopus ID2-s2.0-84988311514
Özet
Irisin is a myokine/adipokine with potential role in obesity and diabetes. The purpose of the present study was to assess irisin levels and its association with insulin resistance and oxidative stress markers in premenopausal normal-weight and obese women. Ten obese (mean body mass index, 32.65±3.04 kg m−2) and 10 normal-weight (23.00±2.23 kg m−2) premenopausal women were involved in the present study. Anthropometric, and body composition parameters, blood chemistry, oxidative stress markers, and irisin concentrations of different groups were measured. Correlation analyses were performed between irisin and other measured parameters. Plasma irisin levels were lower in the obese group than the normal-weight group (p<0.05). Glucose, homeostasis model assessment index (HOMA-IR), and MDA levels in the obese group were higher than that in the normal-weight group (p<0.05). Plasma irisin was negatively correlated with insulin (r=−0.648, p<0.05), HOMA-IR (r=−0.664, p<0.05) and MDA (r=−0.690, p<0.05). These data suggest that irisin levels are decreased with obesity, and irisin may have an antidiabetic and antioxidant effects.
Yazarlar (3)
1
Muaz Belviranli
2
Nilsel Okudan
3
F. Çelik
Anahtar Kelimeler
insulin resistance
irisin
obesity
oxidative stress
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
26
Atıf
3
Yazar
4
Anahtar Kelime