Scopus
YÖKSİS DOI Eşleşti
SJR Q1
Zebrafish optomotor response to second-order motion illustrates that age-related changes in motion detection depend on the activated motion system
Neurobiology of Aging · Ekim 2023
YÖKSİS Kayıtları
Zebrafish optomotor response to second-order motion illustrates that age-related changes in motion detection depend on the activated motion system.
Neurobiology of aging · 2023 SCI-Expanded
Dr. Öğr. Üyesi ELİF TUĞCE KAROĞLU ERAVŞAR →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Aging alters the molecular dynamics of synapses in a sexually dimorphic pattern in zebrafish (Danio rerio)
2017 ISSN: 0197-4580 SCI
Dr. Öğr. Üyesi ELİF TUĞCE KAROĞLU ERAVŞAR →
Short-term dietary restriction maintains synaptic plasticity whereas short-term overfeeding alters cellular dynamics in the aged brain: evidence from the zebrafish model organism
2021 ISSN: 0197-4580 SCI-Expanded Q2
Dr. Öğr. Üyesi ELİF TUĞCE KAROĞLU ERAVŞAR →
The optomotor response of aging zebrafish reveals a complex relationship between visual motion characteristics and cholinergic system
2021 ISSN: 0197-4580 SCI-Expanded Q2
Dr. Öğr. Üyesi ELİF TUĞCE KAROĞLU ERAVŞAR →
Zebrafish optomotor response to second-order motion illustrates that age-related changes in motion detection depend on the activated motion system.
2023 ISSN: 0197-4580 SCI-Expanded
Dr. Öğr. Üyesi ELİF TUĞCE KAROĞLU ERAVŞAR →
Makale Bilgileri
Dergi
Neurobiology of Aging
ISSN01974580
Yayın TarihiEkim 2023
Cilt / Sayfa130 · 12-21
Scopus ID2-s2.0-85164327460
Özet
Various aspects of visual functioning, including motion perception, change with age. Yet, there is a lack of comprehensive understanding of age-related alterations at different stages of motion processing and in each motion system. To understand the effects of aging on second-order motion processing, we investigated optomotor responses (OMR) in younger and older wild-type (AB-strain) and acetylcholinesterase (achesb55/+) mutant zebrafish. The mutant fish with decreased levels of acetylcholinesterase have been shown to have delayed age-related cognitive decline. Compared to previous results on first-order motion, we found distinct changes in OMR to second-order motion. The polarity of OMR was dependent on age, such that second-order stimulation led to mainly negative OMR in the younger group while older zebrafish had positive responses. Hence, these findings revealed an overall aging effect on the detection of second-order motion. Moreover, neither the genotype of zebrafish nor the spatial frequency of motion significantly changed the response magnitude. Our findings support the view that age-related changes in motion detection depend on the activated motion system.
Yazarlar (6)
1
Aysenur Karaduman
2
Elif Tugce Karoglu-Eravsar
3
Utku Kaya
4
Alaz Aydin
5
Michelle M. Adams
6
Hulusi Kafaligonul
ORCID: 0000-0001-5033-4138
Anahtar Kelimeler
Acetylcholinesterase
Aging
Motion detection
Second-order motion
Zebrafish
Kurumlar
Bilkent Üniversitesi
Ankara Turkey
Middle East Technical University (METU)
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey
University of Michigan Medical School
Ann Arbor United States
Scimago Dergi (ISSN Eşleşmesi)
Neurobiology of Aging
Q1
SJR Skoru1,447
H-Index220
YayıncıElsevier Inc.
ÜlkeUnited States
Developmental Biology (Q1)
Geriatrics and Gerontology (Q1)
Neurology (clinical) (Q1)
Neuroscience (miscellaneous) (Q1)
Aging (Q2)
Metrikler
2
Atıf
6
Yazar
5
Anahtar Kelime