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EFFECTS OF SELECTION IN TERMS OF MEAT YIELD TRAITS ON LEPTIN RECEPTOR GENE IN JAPANESE QUAIL LINES

Slovenian Veterinary Research · Ocak 2022

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YÖKSİS Kayıtları
EFFECTS OF SELECTION IN TERMS OF MEAT YIELD TRAITS ON LEPTIN RECEPTOR GENE IN JAPANESE QUAIL LINES
SLOVENIAN VETERINARY RESEARCH · 2022 SCI-Expanded
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Makale Bilgileri

DergiSlovenian Veterinary Research
Yayın TarihiOcak 2022
Cilt / Sayfa59 · 89-98
Erişim🔓 Açık Erişim
Özet This study was carried out to investigate the effects of selection on the single nucleotide polymorphisms (SNPs) in coding sequence of leptin receptor (LEPR) gene and possible associations between SNPs’ and some meat yield traits of Japanese quail lines. Fifteen generations divergently selected two lines (HBW and LBW) for 5-weeks of age body weight and a control were used as materials for this study. A 348-bp part of the LEPR coding region (18th exon) were sequenced in a total of 113 individuals from the three quail lines and shown that the fragments contained four SNPs loci (T490C, C528T, G537A, T571C) and five haplotypes (TTGT, CTGT, TCGT, TCAT, TCAC). T490C replacement caused the missense mutation of phenylalanine to convert to leucine (Phe>Leu). However, other SNPs were synonymous and there were no changes in transcripts. It was determined that the quails with higher phenotypic values were in the TT genotype at the T390C locus. Statistical analyses showed that there were significant differences among the quail lines, SNP alleles and haplotypes in terms of interested phenotypic traits (P<0.05), and also SNP and haplotype distributions changed depending on quail lines (P<0.001). When all results were evaluated together, it was concluded that the fifteen generations of selection caused significant changes in the LEPR gene in terms of economically important traits in Japanese quail lines (C. coturnix japonica).

Yazarlar (6)

1
Kemal Karabağ
2
Sezai Alkan
3
Taki Karslı
4
Cengiz İkten
5
İnci Şahin
6
Mehmet Mendeş

Anahtar Kelimeler

haplotype Japanese quail leptin receptor selection SNP

Kurumlar

Akdeniz Üniversitesi
Antalya Turkey
Çanakkale Onsekiz Mart Üniversitesi
Canakkale Turkey
Ordu Üniversitesi
Ordu Turkey
Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

2
Atıf
6
Yazar
5
Anahtar Kelime