Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Effects of inactive parapoxvirus ovis on Cytokine levels in Rats
Journal of Veterinary Medical Science · Şubat 2016
YÖKSİS Kayıtları
Effects of Inactive Parapoxvirus Ovis on Cytokine Levels in Rats
Journal of Veterinary Medical Science · 2016 SCI-Expanded
DOÇENT IRMAK DİK →
Effects of i inactive parapoxvirus ovis i on cytokine levels in rats
Journal of Veterinary Medical Science · 2016 SSCI
DOÇENT IRMAK DİK →
Effects of inactive parapoxvirus ovis on cytokine levels in rats
Journal of Veterinary Medical Science · 2016 SSCI
PROFESÖR OĞUZHAN AVCI →
Effects of inactive parapoxvirus ovis on cytokine levels in rats
Journal of Veterinary Medical Science · 2016 SCI-Expanded
PROFESÖR OĞUZHAN AVCI →
Makale Bilgileri
DergiJournal of Veterinary Medical Science
Yayın TarihiŞubat 2016
Cilt / Sayfa78 · 129-131
Scopus ID2-s2.0-84956914448
Erişim🔓 Açık Erişim
Özet
The aim of this study is to determine the effects of iPPOV on pro-inflammatory and anti-inflammatory cytokine levels in rats. iPPOV (1 ml/rat) was administered intraperitoneal route to 49 rats, except for 7 rats (Control, 0 group). Serum samples were collected from 7 rats at 1st, 2nd, 4th, 8th, 12th, 16th and 24th hr after treatments. Levels of TNF-α, IL-6, IL-12 and IL-10 were determined using ELISA. Administration of iPPOV stimulated TNF-α (16th and 24th hr) and IL-6 (12th, 16th and 24th hr) synthesis and caused fluctuations in IL-10 and IL-12 concentrations. In conclusion, increased cytokine levels could be attributed to immunomodulatory activity of iPPOV, however, detailed studies are required to fully understand effects of iPPOV on immune system.
Yazarlar (3)
1
Oğuzhan Avci
ORCID: 0000-0001-9299-4695
2
Oya Bulut
3
Irmak Dik
ORCID: 0000-0003-2516-9489
Anahtar Kelimeler
Cytokine
Inactive parapoxvirus ovis
Rat
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
3
Atıf
3
Yazar
3
Anahtar Kelime