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Effect of strategies to increase progesterone levels on fertility of bovine embryo transfer recipients - A meta-analysis

Theriogenology · Şubat 2024

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YÖKSİS Kayıtları
Effect of strategies to increase progesterone levels on fertility of bovine embryo transfer recipients - A meta-analysis
Theriogenology · 2024 SCI-Expanded
DOÇENT KÜBRA KARAKAŞ ALKAN →
Effect of strategies to increase progesterone levels on fertility of bovine embryo transfer recipients - A meta-analysis
Theriogenology · 2024 SCI-Expanded
DOÇENT HASAN ALKAN →
Effect of strategies to increase progesterone levels on fertility of bovine embryo transfer recipients - A meta-analysis
Theriogenology · 2024 SCI-Expanded
DOÇENT FATMA SATILMIŞ →

Makale Bilgileri

DergiTheriogenology
Yayın TarihiŞubat 2024
Cilt / Sayfa215 · 177-186
Özet The pregnancy rate following embryo transfer (ET) is a very important factor in the success of embryo production programs. Different strategies were therefore developed to increase pregnancy rates. The aim of this meta-analysis was to investigate the effects of hormone treatments used to increase the success of embryo transfer programs on pregnancy rates. A meta-analysis was performed of 46 trials from 39 publications involving treated (n = 7856) and control (n = 6663) cattle. The meta-analysis explained the effect size with its 95 % confidence interval (CI) for pregnancy per embryo transfer (P/ET) after hormonal treatment under different moderators. Hormonal support was found to increase P/ET compared to the control group (P < 0.05). However, GnRH treatment was found to increase P/ET by approximately 4.3 % and hCG treatment by 8.0 %. Progesterone supplementation was not found to have a statistically significant effect on P/ET. In addition, GnRH treatment significantly increased P/ET when used to transfer in vitro or frozen-thawed embryos or in studies using cows as recipients. It was observed that hCG treatment had a positive effect on P/ET according to all moderators. Progesterone supplementation significantly increased P/ET when frozen embryos were transferred and reduced P/ET, especially in publications where fresh or in vitro produced embryos were transferred or cows were used as recipients. The results of this meta-analysis showed that the use of GnRH, and hCG, in bovine embryo transfer programs increased P/ET, whereas the use of progesterone had no effect on P/ET. However, it was found that P/ET could increase/decrease depending on the moderator.

Yazarlar (8)

1
Hasan Alkan
ORCID: 0000-0001-8332-5334
2
Mustafa Agah Tekindal
ORCID: 0000-0002-4060-7048
3
Mehmet Akif Demirel
4
Berrak Isik Soyturk
5
Maide Golbasi
6
Yunus Emre Deniz
7
Fatma Satilmiş
8
Kubra Karakas Alkan

Anahtar Kelimeler

Cattle Embryo production Hormonal therapy P/ET

Kurumlar

İzmir Kâtip Çelebi Üniversitesi
Izmir Turkey
Muğla Sıtkı Koçman Üniversitesi
Mugla Turkey
Selçuk Üniversitesi
Selçuklu Turkey