Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Effect of Static Magnetic Field on Oxidant/Antioxidant Parameters in Cancerous and Noncancerous Human Gastric Tissues
Scientifica · Ocak 2016
YÖKSİS Kayıtları
Effect of Static Magnetic Field on Oxidant Antioxidant Parameters in Cancerous and Noncancerous Human Gastric Tissues
Scientifica · 2016 ESCI
PROFESÖR BAHADIR ÖZTÜRK →
Makale Bilgileri
DergiScientifica
Yayın TarihiOcak 2016
Cilt / Sayfa2016
Scopus ID2-s2.0-85015431396
Erişim🔓 Açık Erişim
Özet
Aim. To investigate the effects of static magnetic field (SMF) on oxidant and antioxidant parameters of the cancerous and noncancerous human gastric tissues. Materials and Methods. Gastric tissues obtained from patients with gastric cancer were used in the study. SMF was created by using two static magnets. Before and after treatment with SMF, oxidant and antioxidant parameters were measured in the tissue samples. Results. In the cancerous tissue, superoxide dismutase (SOD) activity was found higher and malondialdehyde (MDA) level was found lower as compared with noncancerous tissue. SMF affects oxidant/antioxidant parameters differently in the cancerous and noncancerous tissues. In this regard, SMF causes increase in SOD activity and decrease in MDA level in the noncancerous tissue. However, it decreases SOD and glutathione peroxidase (GSH-Px) activities and increases MDA level and catalase (CAT) activity in the cancerous tissue. There were no differences between nitric oxide (NO) and nitric oxide synthase (NOS) parameters in or among the cancerous and noncancerous tissues. Conclusions. SMF accelerates peroxidation reactions possibly by suppressing SOD and GSH-Px enzymes in the cancerous gastric tissue. This event caused by SMF might play part in the death of cancer cells, which may be a good supportive vehicle for the cancer therapy.
Yazarlar (4)
1
Bahadır Öztürk
2
Zahide Esra Durak
3
Süleyman Büber
4
Ender Hilmi Kocaoǧlu
Kurumlar
Ankara Üniversitesi
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey
The Laboratory of Turkish Public Health Institution
Ankara Turkey
Metrikler
7
Atıf
4
Yazar