Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Effect of injectable platelet-rich fibrin (i-PRF) on the rate of tooth movement: A randomized clinical trial
Angle Orthodontist · Mayıs 2021
YÖKSİS Kayıtları
Effect of injectable platelet-rich fibrin (i-PRF) on the rate of tooth movement: A randomized clinical trial
The Angle Orthodontist · 2021 SCI-Expanded
PROFESÖR BAHADIR ÖZTÜRK →
Effect of injectable platelet-rich fibrin (i-PRF) on the rate of tooth movement: A randomized clinical trial
The Angle Orthodontist · 2021 SCI-Expanded
PROFESÖR SEMA HAKKI →
Makale Bilgileri
DergiAngle Orthodontist
Yayın TarihiMayıs 2021
Cilt / Sayfa91 · 285-292
Scopus ID2-s2.0-85105835271
Erişim🔓 Açık Erişim
Özet
Objectives: To evaluate the efficiency of injectable platelet-rich fibrin (i-PRF) in accelerating canine tooth movement and to examine levels of the matrix metalloproteinase-8 (MMP-8), interleukin-1b (IL-1b), receptor activator of nuclear factor kappa-light-chain-enhancer of activated B cells ligand (RANKL), and osteoprotegerin (OPG) in the gingival crevicular fluid during orthodontic treatment. Materials and Methods: Twenty patients (mean age ¼ 21.4 6 2.9 years) with Class II Division 1 malocclusion were included in a split-mouth study. The treatment plan for all patients was extraction of maxillary first premolars followed by canine distalization with closed-coil springs using 150 g of force on each side. The study group received i-PRF two times, with a 2-week interval, on one side of the maxilla. The contralateral side served as the control and did not receive i-PRF. Maxillary canine tooth movement was measured at five time points (T1–T5) on each side. Also, the activity of inflammatory cytokines was evaluated at three time points in the gingival crevicular fluid samples. Results: There was a significant difference in canine tooth movement between the two groups (P, .001). i-PRF significantly increased the rate of tooth movement, and stimulation in the levels of inflammatory cytokines supported this result (P, .001). The levels of cytokines changed in both groups between T1 and T2. The IL-1b, MMP8, and RANKL values were significantly increased in the study group compared with the control group, while the OPG values were significantly decreased. Conclusions: i-PRF-facilitated orthodontics is an effective and safe treatment modality to accelerate tooth movement, and this method can help shorten orthodontic treatment duration. (Angle Orthod. 2021;91:285–292.)
Yazarlar (5)
1
Emire Aybuke Erdur
2
Kuter Karakaslı
3
Elif Öncü
ORCID: 0000-0002-5774-4604
4
Bahadır Öztürk
5
Sema S. Hakkı
Anahtar Kelimeler
Injectable platelet-rich fibrin
I-PRF
Rate of tooth movement
Kurumlar
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
37
Atıf
5
Yazar
3
Anahtar Kelime