Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q1
The association of premature ovarian failure with ventricular repolarization dynamics evaluated by QT dynamicity
Europace · Kasım 2013
YÖKSİS Kayıtları
The association of premature ovarian failure with ventricular repolarization dynamics evaluated by QT dynamicity
Europace · 2013 SCI-Expanded
Doç. Dr. KADRİ MURAT GÜRSES →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Predictors of left atrial volume index reduction following cryoballoon-based pulmonary vein isolation
2016 ISSN: 1099-5129 SCI-Expanded
Doç. Dr. KADRİ MURAT GÜRSES →
Safety and efficacy outcomes in patients undergoing pulmonary vein isolation with second generation cryoballoon
2015 ISSN: 1099-5129 SCI-Expanded 26 atıf
Doç. Dr. KADRİ MURAT GÜRSES →
M2 muscarinic acetylcholine receptor autoantibody levels predict left atrial fibrosis severity in paroxysmal lone atrial fibrillation patients undergoing cryoablation
2015 ISSN: 1099-5129 SCI-Expanded 8 atıf
Doç. Dr. KADRİ MURAT GÜRSES →
Predictors of left atrial volume index reduction following cryoballoon based pulmonary vein isolation
2016 ISSN: 1099-5129 SCI-Expanded
Doç. Dr. MUHAMMED ULVİ YALÇIN →
Safety and efficacy outcomes in patients undergoing pulmonary vein isolation with second generation cryoballoon
2015 ISSN: 1099-5129 SCI-Expanded
Doç. Dr. MUHAMMED ULVİ YALÇIN →
M2 muscarinic acetylcholine receptor autoantibody levels predict left atrial fibrosis severity in paroxysmal lone atrial fibrillation patients undergoing cryoablation
2015 ISSN: 1099-5129 SCI-Expanded
Doç. Dr. MUHAMMED ULVİ YALÇIN →
The association of premature ovarian failure with ventricular repolarization dynamics evaluated by QT dynamicity
2013 ISSN: 1099-5129 SCI-Expanded
Doç. Dr. KADRİ MURAT GÜRSES →
Makale Bilgileri
Dergi
Europace
ISSN10995129
Yayın TarihiKasım 2013
Cilt / Sayfa15 · 1657-1663
Scopus ID2-s2.0-84907299829
Erişim🔓 Açık Erişim
Özet
Aims The association between premature ovarian failure (POF) and cardiovascular diseases has been investigated in a few studies, but none have looked at ventricular repolarization abnormalities in these patients. In this study, we aimed to evaluate the ventricular repolarization by QT dynamicity in patients with POF. Methods and results We enrolled 26 female patients (mean age 37.5 ± 10.1 years) with primary POF and 31 healthy female subjects (mean age 37.5 ± 9.0 years). The linear regression slopes of the QT interval measured to the apex and to the end of the T-wave plotted against RR intervals (QTapex/RR and QTend/RR slopes, respectively) were calculated from 24 h Holter recordings using a standard algorithm. QTapex/RR and QTend/RR slopes were more steeper in the POF patients in contrary to healthy control subjects (QTapex/RR = 0.184 ± 0.022 vs. 0.131 ± 0.019, P < 0.001; QTend/RR = 0.164 ± 0.021 vs. 0.128 ± 0.018, P < 0.001). Pearson's correlation analyses revealed a stronger negative correlation between oestradiol (E2) and QTapex/RR (r = -0.715, P < 0.001). There was also a moderate negative correlation between E2 and QTend/RR (r = -0.537, P < 0.001). Serum follicle-stimulating hormone level was positively correlated with QTapex/RR (r = 0.681, P < 0.001) and QTend/RR (r = 0.531, P < 0.001). Conclusions Our study results suggest that QT dynamicity is impaired in patients with POF despite the absence of overt cardiovascular involvement. Further studies are needed to elucidate the prognostic significance and clinical implications of impaired ventricular repolarization in patients with POF.
Yazarlar (10)
1
Ugur Canpolat
ORCID: 0000-0002-4250-1706
2
Lale Tokgozoglu
3
Hikmet Yorgun
4
Ergün Barlşkaya
5
Kadri Murat Gurses
6
Levent Sahiner
7
Gürkan Bozdaǧ
8
Giray Kabakçl
9
Mehmet Ali Oto
10
Kudret Aytemir
Anahtar Kelimeler
Premature ovarian failure
QT dynamicity
Ventricular repolarization
Kurumlar
Hacettepe Üniversitesi
Ankara Turkey
Scimago Dergi (ISSN Eşleşmesi)
Europace
Q1
SJR Skoru3,446
H-Index145
YayıncıOxford University Press
ÜlkeUnited Kingdom
Cardiology and Cardiovascular Medicine (Q1)
Physiology (medical) (Q1)
Metrikler
7
Atıf
10
Yazar
3
Anahtar Kelime