Scopus
YÖKSİS DOI Eşleşti
SJR Q2
Effects of persistent atrial fibrillation on serum galectin-3 levels
American Journal of Cardiology · Mart 2015
YÖKSİS Kayıtları
Effects of Persistent Atrial Fibrillation on Serum Galectin 3 Levels
The American Journal of Cardiology · 2015 SCI 10 atıf
Doç. Dr. KADRİ MURAT GÜRSES →
Effects of Persistent Atrial Fibrillation on Serum Galectin 3 Levels
The American Journal of Cardiology · 2015 SCI
Doç. Dr. MUHAMMED ULVİ YALÇIN →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Monocyte Toll Like Receptor Expression in Patients With Atrial Fibrillation
2016 ISSN: 00029149 SCI
Doç. Dr. KADRİ MURAT GÜRSES →
Enhanced Platelet Toll like Receptor 2 and 4 Expression in Acute Coronary Syndrome and Stable Angina Pectoris
2015 ISSN: 00029149 SCI 1 atıf
Doç. Dr. KADRİ MURAT GÜRSES →
Effects of Persistent Atrial Fibrillation on Serum Galectin 3 Levels
2015 ISSN: 00029149 SCI 10 atıf
Doç. Dr. KADRİ MURAT GÜRSES →
Monocyte Toll Like Receptor Expression in Patients With Atrial Fibrillation
2016 ISSN: 00029149 SCI
Doç. Dr. MUHAMMED ULVİ YALÇIN →
Effects of Persistent Atrial Fibrillation on Serum Galectin 3 Levels
2015 ISSN: 00029149 SCI
Doç. Dr. MUHAMMED ULVİ YALÇIN →
Left Ventricular Function by Echocardiography Tissue Doppler Imaging and Carotid Intima Media Thickness in Obese Adolescents With Nonalcoholic Fatty Liver Disease
2013 ISSN: 00029149 SCI-Expanded
Prof. Dr. AHMET SERT →
Comparison of Increased Aspirin Dose Versus Combined Aspirin Plus Clopidogrel Therapy in Patients With Diabetes Mellitus and Coronary Heart Disease and Impaired Antiplatelet Response to Low-Dose Aspirin
2008 ISSN: 00029149 SCI
Prof. Dr. NAZİF AYGÜL →
Enhanced Platelet Toll-like Receptor 2 and 4 Expression in Acute Coronary Syndrome and Stable Angina Pectoris
2015 ISSN: 00029149 SCI-Expanded
Doç. Dr. MUHAMMED ULVİ YALÇIN →
Effects of Inspiratory Muscle Training in Patients With Pulmonary Hypertension
2023 ISSN: 0002-9149 SCI-Expanded Q3
Doç. Dr. İSMAİL ÖZSOY →
Makale Bilgileri
ISSN00029149
Yayın TarihiMart 2015
Cilt / Sayfa115 · 647-651
Scopus ID2-s2.0-84922994503
Özet
Galectin-3 is known to play an important role in a number of fibrotic conditions, including cardiac fibrosis. Many studies have focused on the association between galectin-3 levels and cardiac fibrosis in heart failure. However, the role of galectin-3 in the pathogenesis of atrial fibrillation (AF) has not been evaluated thoroughly yet. The aim of this study was to determine whether serum galectin-3 levels were elevated in patients with AF and preserved left ventricular function. Seventy-six patients with paroxysmal or persistent AF and preserved left ventricular systolic function and 75 age- and gender-matched control subjects were enrolled in this observational study. Galectin-3 levels were measured by enzyme-linked immunosorbent assay. Serum galectin-3 (median 0.6 ng/ml [interquartile range 0.2 to 1.4] vs 0.5 ng/ml [interquartile range 0.1 to 0.7], p <0.001) and left atrial volume index (LAVI) (mean 29.5 ± 3.5 vs 26.5 ± 2.5 ml/m2, p <0.001) were significantly greater in patients with AF compared with the control group. Serum galectin-3 levels were also significantly higher in patients with persistent AF than those with paroxysmal AF (median 0.8 ng/ml [interquartile range 0.4 to 1.4] vs 0.5 ng/ml [interquartile range 0.2 to 0.9], p <0.001). Multivariate regression analysis demonstrated that serum galectin-3 (odds ratio 87.53, 95% confidence interval 6.06 to 1,265.03, p = 0.001) and LAVI (odds ratio 1.38, 95% confidence interval 1.19 to 1.60, p <0.001) were independent predictors of AF. Only LAVI was independently correlated with serum galectin-3 levels in patients with AF in linear regression analysis. In conclusion, serum galectin-3 is significantly elevated and is also significantly correlated with LAVI in patients with AF with preserved left ventricular function.
Yazarlar (13)
1
Kadri Murat Gurses
2
Muhammed Ulvi Yalçın
3
Duygu Kocyigit
4
Hande Canpinar
5
Banu Evranos
6
Hikmet Yorgun
7
Mehmet Levent Şahiner
8
Ergün Barış Kaya
9
Necla Ozer
10
Lale Tokgozoglu
11
Mehmet Ali Oto
12
Dicle Guc
13
Kudret Aytemir
Kurumlar
Hacettepe Üniversitesi
Ankara Turkey
Scimago Dergi (ISSN Eşleşmesi)
American Journal of Cardiology
Q2
SJR Skoru0,933
H-Index243
YayıncıElsevier Inc.
ÜlkeUnited States
Cardiology and Cardiovascular Medicine (Q2)
Metrikler
64
Atıf
13
Yazar