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Periatrial epicardial adipose tissue thickness is an independent predictor of atrial fibrillation recurrence after cryoballoon-based pulmonary vein isolation

Journal of Cardiovascular Computed Tomography · Temmuz 2015

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YÖKSİS Kayıtları
Periatrial epicardial adipose tissue thickness is an independent predictor of atrial fibrillation recurrence after cryoballoon based pulmonary vein isolation
Journal of Cardiovascular Computed Tomography · 2015 SCI-Expanded 3 atıf
DOÇENT KADRİ MURAT GÜRSES →
Periatrial epicardial adipose tissue thickness is an independent predictor of atrial fibrillation recurrence after cryoballoon based pulmonary vein isolation
Journal of Cardiovascular Computed Tomography · 2015 SCI-Expanded
DOÇENT MUHAMMED ULVİ YALÇIN →

Makale Bilgileri

DergiJournal of Cardiovascular Computed Tomography
Yayın TarihiTemmuz 2015
Cilt / Sayfa9 · 295-302
Özet Background: Epicardial adipose tissue (EAT) is a metabolically active fat depot. Studies have investigated the effect of EAT thickness on outcomes of radiofrequency catheter ablation of atrial fibrillation (AF). However, data on the relationship between EAT thickness and outcome of cryoballoon-based pulmonary vein isolation (PVI) are lacking. Objective: In this study, we investigate the association between EAT thickness and AF recurrence after cryoballoon-based PVI. Methods: Patients with symptomatic paroxysmal or persistent AF despite ≥1 antiarrhythmic drug(s) were scheduled for cryoballoon-based PVI for AF per the recent recommendations. Periatrial, periventricular, and total EAT thickness measurements were obtained from preprocedural multidetector CT scans. Results: A total of 249 patients (55.6 ± 10.7 years; 48.2% male; 18.5% persistent AF) were involved in the study. Patients were followed-up for 29 months (8-48 months). When blanking period was considered, freedom from AF after the ablation procedure was 75.9% at a median follow-up of 29 months. Total periatrial EAT thickness (18.1 ± 6.2 vs 14.7 ± 4.7 mm; P < .001) was greater in patients with late AF recurrence when compared to those without. On the other hand, periventricular or total EAT thickness measurements did not differ between both groups (. P > .05). Multivariate Cox proportional hazard regression analysis showed that periatrial EAT thickness (hazard ratio, 1.086; P = .001) and left atrial volume index (hazard ratio, 1.144; P < .001) were independent predictors for late AF recurrence. Conclusion: Quantification of EAT thickness from preprocedural multidetector CT scans may serve as a beneficial parameter for prediction of AF recurrence after cryoballoon-based PVI.

Yazarlar (13)

1
Duygu Kocyigit
2
Kadri Murat Gurses
3
Muhammed Ulvi Yalçın
4
Gamze Turk
5
Banu Evranos
6
Hikmet Yorgun
7
Mehmet Levent Şahiner
8
Ergün Barış Kaya
9
Tuncay Hazirolan
10
Lale Tokgozoglu
11
Mehmet Ali Oto
12
Necla Ozer
13
Kudret Aytemir

Anahtar Kelimeler

Ablation Atrial fibrillation Cardiac computed tomography Epicardial adipose tissue Outcome

Kurumlar

Hacettepe Üniversitesi
Ankara Turkey
Konya Meram Training and Research Hospital
Konya Turkey
T. C. Sağlık Bakanlığı Hakkari Devlet Hastanesi
Hakkari Turkey

Metrikler

40
Atıf
13
Yazar
5
Anahtar Kelime

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