Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q1
Serum galectin-3 level as a marker of thrombogenicity in atrial fibrillation
Journal of Clinical Laboratory Analysis · Kasım 2017
YÖKSİS Kayıtları
Serum galectin-3 level as a marker of thrombogenicity in atrial fibrillation
Journal of Clinical Laboratory Analysis · 2017 SCI-Expanded
Doç. Dr. MUHAMMED ULVİ YALÇIN →
Serum galectin-3 level as a marker of thrombogenicity in atrial fibrillation
Journal of Clinical Laboratory Analysis · 2017 SCI
Doç. Dr. KADRİ MURAT GÜRSES →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Serum and Saliva Levels of Ischemia Modified Albumin in Patients with Acute Myocardial Infarction
2013 ISSN: 08878013 SCI-Expanded
Prof. Dr. FATMA HÜMEYRA YERLİKAYA AYDEMİR →
Evaluation of Netrin 1 Levels and Albuminuria in Patients With Diabetes
2016 ISSN: 08878013 SCI
Prof. Dr. ALİ ÜNLÜ →
Serum galectin-3 level as a marker of thrombogenicity in atrial fibrillation
2017 ISSN: 08878013 SCI-Expanded Q3
Doç. Dr. MUHAMMED ULVİ YALÇIN →
Evaluation of Netrin-1 Levels and Albuminuria in Patients With Diabetes
2016 ISSN: 08878013 SCI-Expanded
Prof. Dr. KAMİLE MARAKOĞLU →
Serum galectin-3 level as a marker of thrombogenicity in atrial fibrillation
2017 ISSN: 08878013 SCI
Doç. Dr. KADRİ MURAT GÜRSES →
Enhanced serum levels of matrix Gla protein and bone morphogenetic protein in acute coronary syndrome patients
2018 ISSN: 0887-8013 SCI
Doç. Dr. KADRİ MURAT GÜRSES →
Investigation of the Levels of Serum Amyloid A, YKL-40, and Pentraxin-3 in Patients with Familial Mediterranean Fever
2016 ISSN: 08878013 SCI
Prof. Dr. YASEMİN COŞKUN YAVUZ →
The importance of serum biglycan levels as a fibrosis marker in patients with chronic hepatitis B
2016 ISSN: 0887-8013 SCI-Expanded Q3
Prof. Dr. RAFİYE ÇİFTÇİLER →
Makale Bilgileri
ISSN08878013
Yayın TarihiKasım 2017
Cilt / Sayfa31
Scopus ID2-s2.0-85015211819
Erişim🔓 Açık Erişim
Özet
Background: Left atrial appendage flow velocity (LAAFV) and presence of spontaneous echo contrast (SEC) have been reported to be predictors of thromboembolism in atrial fibrillation (AF) patients. Galectin-3 is a biomarker reflecting pro-inflammatory status, whose role in AF has recently drawn attention, particularly in persistent AF population. Aim: In this study we aimed to investigate the association between serum galectin-3 levels and echocardiographic predictors of thromboembolism in persistent AF patients. Methods: We included 65 persistent AF patients (55.50±10.67 years, 46.15% male). Transesophageal echocardiography (TEE) was performed to assess LAAFV and presence of left atrial (LA)/LA appendage (LAA)-located SEC and thrombus prior to direct current cardioversion or catheter ablation for AF. Results: Median galectin-3 level was 0.63 ng/mL. Serum galectin-3 levels were significantly correlated with LAAFV (r=−.440, P<.001). Serum galectin-3 levels were associated with presence of SEC (P<.001), and LA thrombus (P=.008). Receiver operating characteristic analysis revealed that a serum galectin-3 greater or equal to the cut-off value of 0.69 predicted presence of SEC with a sensitivity and specificity of 91.00% and 79.00%, respectively (P<.001). Conclusion: In conclusion, in the setting of persistent AF, serum galectin-3 levels are associated with presence of SEC and LAAFV on TEE. Our findings suggest that serum galectin-3 level may have a place in thromboembolism risk stratification in persistent AF patients.
Yazarlar (10)
1
Duygu Kocyigit
2
Kadri Murat Gurses
3
Muhammed Ulvi Yalçın
4
Hande Canpinar
5
Ugur Canpolat
ORCID: 0000-0002-4250-1706
6
Banu Evranos
7
Hikmet Yorgun
8
Necla Ozer
9
Dicle Guc
10
Kudret Aytemir
Anahtar Kelimeler
atrial fibrillation
galectin-3
left atrial appendage flow velocity
transesophageal echocardiography
Kurumlar
Hacettepe Üniversitesi
Ankara Turkey
Konya Meram Training and Research Hospital
Konya Turkey
Selçuk Tip Fakültesi
Konya Turkey
Scimago Dergi (ISSN Eşleşmesi)
Journal of Clinical Laboratory Analysis
Q1
OA
SJR Skoru0,847
H-Index71
YayıncıWiley-Liss Inc.
ÜlkeUnited States
Medical Laboratory Technology (Q1)
Biochemistry (medical) (Q2)
Clinical Biochemistry (Q2)
Hematology (Q2)
Immunology and Allergy (Q2)
Microbiology (medical) (Q2)
Public Health, Environmental and Occupational Health (Q2)
Metrikler
14
Atıf
10
Yazar
4
Anahtar Kelime