Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Serum galectin-3 level predicts early recurrence following successful direct-current cardioversion in persistent atrial fibrillation patients
Turk Kardiyoloji Dernegi Arsivi · Ocak 2019
YÖKSİS Kayıtları
Serum galectin-3 level predicts early recurrence following successful direct current cardioversion in persistent atrial fibrillation patients.
Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology · 2019 ESCI (Emerging Sources Citation Index)
DOÇENT MUHAMMED ULVİ YALÇIN →
Serum galectin-3 level predicts early recurrence following successful direct current cardioversion in persistent atrial fibrillation patients.
Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology · 2019 ESCI (Emerging Sources Citation Index)
DOÇENT KADRİ MURAT GÜRSES →
Makale Bilgileri
DergiTurk Kardiyoloji Dernegi Arsivi
Yayın TarihiOcak 2019
Cilt / Sayfa47 · 564-571
Scopus ID2-s2.0-85072916806
Erişim🔓 Açık Erişim
Özet
Objective: Atrial structural remodeling has been suggested to contribute to atrial fibrillation (AF) recurrence following direct-current cardioversion (DCCV). The role of several inflammatory and extracellular matrix turnover markers in AF recurrence following DCCV has been investigated. However, data on the impact of galectin-3, which is known to play a role in various fibrotic conditions, including cardiac fibrosis are lacking. The aim of this study was to demonstrate the predictive role of serum galectin-3 levels in AF recurrence following successful DCCV. Methods: A total of 90 persistent AF patients who were scheduled for DCCV were prospectively enrolled. Serum samples were assayed to determine pre-DCCV galectin-3 levels using the enzyme-linked immunosorbent assay method. Patients were followed up for 3 months for AF recurrence. Results: Of 90 persistent AF patients (mean age: 55.33±7.94 years; 53.33% male) who underwent successful DCCV, 28 (31.11%) experienced early AF recurrence within 3 months. Patients with AF recurrence had a greater left atrial volume index (LAVI) (33.35± 2.45 mL/m2 vs. 29.21±3.08 mL/m2; p<0.001) and serum galectin-3 levels were higher (0.88 ng/mL [min-max: 0.52-1.32] vs. 0.60 ng/mL [min-max: 0.38-0.91]; p<0.001). In multivariate analysis, the number of DCCV attempts (hazard ratio [HR]: 1.879, 95% confidence interval [CI]: 1.052-3.355; p=0.033), LAVI (HR: 1.180, 95% CI: 1.028-1.354; p=0.018), and serum galectin-3 level (HR: 11.933, 95% CI: 1.220-116.701; p=0.033) were found to be independently associated with early AF recurrence following successful DCCV. Conclusion: Circulating levels of galectin-3 may have an association with early AF recurrence following DCCV.
Yazarlar (9)
1
Kadri Murat Gurses
2
Muhammed Ulvi Yalçın
3
Duygu Kocyigit
4
Hande Canpinar
5
Ahmet Hakan Ateş
6
Ugur Canpolat
ORCID: 0000-0002-4250-1706
7
Hikmet Yorgun
8
Dicle Guc
9
Kudret Aytemir
Anahtar Kelimeler
Atrial fibrillation
Electrical cardioversion
Galectin-3
Remodeling
Kurumlar
Aydin Adnan Menderes University
Aydin Turkey
Dinar Devlet Hastanesi
Dinar Turkey
Hacettepe Üniversitesi
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
13
Atıf
9
Yazar
4
Anahtar Kelime