Scopus
YÖKSİS Eşleşti
QT interval alterations in epilepsy: A thorough investigation between epilepsy subtypes
Journal of Clinical Neuroscience · Ekim 2022
YÖKSİS Kayıtları
QT interval alterations in epilepsy: A thorough investigation between epilepsy subtypes
Journal of Clinical Neuroscience · 2022 SCI-Expanded
DOÇENT KADRİ MURAT GÜRSES →
Makale Bilgileri
DergiJournal of Clinical Neuroscience
Yayın TarihiEkim 2022
Cilt / Sayfa104 · 113-117
Scopus ID2-s2.0-85136484772
Özet
Objectives: Cardiac disturbances and rhythm abnormalities which potentially lead sudden unexpected death in epilepsy, have been extensively studied in focal epilepsies. However, studies including generalized epilepsies are scarce and it is not clear whether electrocardiogram parameters reflecting vulnerability to ventricular arrhythmias differ between these groups. Methods: Medical records of patients who were followed in epilepsy department of a tertiary center between October 2015 and September 2016 were retrospectively reviewed. 66 generalized and 64 focal epilepsy patients with eligible electrophysiological data were analyzed. QTc interval, QTcd and other electrocardiographic indices were compared between patients with focal vs generalized epilepsy. Another analysis was performed in order to disclose any difference between patients with epilepsy (n:130) and psychogenic non-epileptic seizures. A two-tailed p value < 0.05 was considered significant. Results: There was no difference in terms of QTc and QTcd between patients with focal and generalized epilepsy [median: 406 ms vs 404 ms, p = 0.119; and median: 46 ms vs 44 ms, p = 0.497, respectively]. However patients with epilepsy were found to have longer QTc and QTcd when compared to ones with psychogenic non-epileptic seizures (p = 0.035 and p < 0.001, respectively). Conclusion: Current findings demonstrate that patients with epilepsy have longer QTc and QTcd than patients with pure psychogenic non-epileptic seizures. Since there was no difference between patients with focal and generalized epilepsy; QTc interval, QTcd and potential susceptibility to cardiac arrhythmias as a result, could be a consequence of epilepsy itself regardless of origin.
Yazarlar (6)
1
Asli Akyol Gurses
ORCID: 0000-0002-3106-7190
2
Emine Genc
3
Kadri Murat Gurses
4
Taylan Altiparmak
5
Irem Yildirim
6
Bulent Oguz Genc
Anahtar Kelimeler
Cardiac arrhythmia
ECG
Epilepsy
Focal epilepsy
Generalized epilepsy
Kurumlar
Gazi University, Faculty of Medicine
Ankara Turkey
Konya Meram Training and Research Hospital
Konya Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Metrikler
2
Atıf
6
Yazar
5
Anahtar Kelime