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Design of Xylose-Based Semisynthetic Polyurethane Tissue Adhesives with Enhanced Bioactivity Properties

ACS Applied Materials and Interfaces · Şubat 2016

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YÖKSİS Kayıtları
Design of Xylose-Based Semisynthetic Polyurethane Tissue Adhesives with Enhanced Bioactivity Properties
ACS APPLIED MATERIALS INTERFACES · 2016 SCI
Dr. Öğr. Üyesi MERVE GÖKŞİN KARAASLAN TUNÇ →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 16 kaydı bulundu.

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Photothermal Antibacterial and Antibiofilm Activity of Black Phosphorus/Gold Nanocomposites against Pathogenic Bacteria
2020 ISSN: 1944-8244 SCI-Expanded Q1
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Photothermal Antibacterial and Antibiofilm Activity of Black Phosphorus/Gold Nanocomposites against Pathogenic Bacteria
2020 ISSN: 1944-8244 SCI-Expanded
Dr. Öğr. Üyesi FATİH SEVGİ →
Design of Xylose-Based Semisynthetic Polyurethane Tissue Adhesives with Enhanced Bioactivity Properties
2016 ISSN: 1944-8244 SCI
Dr. Öğr. Üyesi MERVE GÖKŞİN KARAASLAN TUNÇ →
Fast Curing Multifunctional Tissue Adhesives of Sericin-Based Polyurethane-Acrylates for Sternal Closure
2022 ISSN: 1944-8244 SCI-Expanded Q1
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Viologen-Based Covalent Organic Frameworks toward Metal-Free Highly Efficient Photocatalytic Hydrogen Evolution
2023 ISSN: 1944-8244 SSCI Q1
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Eco-Friendly Boost for Perovskite Photovoltaics: Harnessing Cellulose-Modified SnO2 as a High-Performance Electron Transporting Material
2023 ISSN: 1944-8244 SCI-Expanded Q1
Doç. Dr. TEOMAN ÖZTÜRK →
Viologen-Based Covalent Organic Frameworks toward Metal-Free Highly Efficient Photocatalytic Hydrogen Evolution
2023 ISSN: 1944-8244 SCI-Expanded Q1
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Sensing Volatile Pollutants with Spin-Coated Films Made of Pillar[5]arene Derivatives and Data Validation via Artificial Neural Networks
2024 ISSN: 1944-8244 SCI-Expanded Q1
Prof. Dr. AHMED NURİ KURŞUNLU →
Sensing volatile pollutants with spin-coated films made of pillar[5]arene derivatives and data validation via artificial neural networks
2024 ISSN: 1944-8244 SCI-Expanded Q1
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Makale Bilgileri

Dergi ACS Applied Materials and Interfaces
ISSN19448244
Yayın TarihiŞubat 2016
Cilt / Sayfa8 · 4456-4466
DOI10.1021/acsami.5b12279
Scopus ID2-s2.0-84962528552
Özet Developing biocompatible tissue adhesives with high adhesion properties is a highly desired goal of the tissue engineering due to adverse effects of the sutures. Therefore, our work involves synthesis, characterization, adhesion properties, protein adsorption, in vitro biodegradation, in vitro and in vivo biocompatibility properties of xylose-based semisynthetic polyurethane (NPU-PEG-X) bioadhesives. Xylose-based semisynthetic polyurethanes were developed by the reaction among 4,4′-methylenebis(cyclohexyl isocyanate) (MCI), xylose and polyethylene glycol 200 (PEG). Synthesized polyurethanes (PUs) showed good thermal stability and high adhesion strength. The highest values in adhesion strength were measured as 415.0 ± 48.8 and 94.0 ± 2.8 kPa for aluminum substrate and muscle tissue in 15% xylose containing PUs (NPU-PEG-X-15%), respectively. The biodegradation of NPU-PEG-X-15% was also determined as 19.96 ± 1.04% after 8 weeks of incubation. Relative cell viability of xylose containing PU was above 86%. Moreover, 10% xylose containing NPU-PEG-X (NPU-PEG-X-10%) sample has favorable tissue response, and inflammatory reaction between 1 and 6 weeks implantation period. With high adhesiveness and biocompatibility properties, NPU-PEG-X can be used in the medical field as supporting materials for preventing the fluid leakage after abdominal surgery or wound closure.

Yazarlar (9)

1
Sevgi Balcioglu
ORCID: 0000-0003-0724-4772
2
Hakan Parlakpinar
ORCID: 0000-0001-9497-3468
3
Nigar Vardi
ORCID: 0000-0003-0576-1696
4
Emir Baki Denkbas
5
Merve Gökşin Karaaslan
6
Selam Gulgen
7
E. Taslidere
8
Suleyman Koytepe
ORCID: 0000-0002-4788-278X
9
Burhan Ates
ORCID: 0000-0001-6080-229X

Anahtar Kelimeler

biocompatibility polyurethane semisynthetic materials tissue adhesive xylose

Kurumlar

Hacettepe Üniversitesi
Ankara Turkey
Inönü Üniversitesi
Malatya Turkey
Scimago Dergi (ISSN Eşleşmesi)
ACS Applied Materials and Interfaces
Q1 OA
SJR Skoru1,921
H-Index334
YayıncıAmerican Chemical Society
ÜlkeUnited States
Materials Science (miscellaneous) (Q1)
Medicine (miscellaneous) (Q1)
Nanoscience and Nanotechnology (Q1)
Dergi sayfasına git

Metrikler

52
Atıf
9
Yazar
5
Anahtar Kelime

Sistemimizdeki Yazarlar

MK
MERVE GÖKŞİN KARAASLAN TUNÇ
Dr. Öğr. Üyesi

Hızlı Erişim

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