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BIO-INSPIRED MAGNETIC BEADS FOR ISOLATION OF SPERM FROM HETEROGENOUS SAMPLES IN FORENSIC APPLICATIONS

Forensic Science International Genetics · Mayıs 2021

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YÖKSİS Kayıtları
BIO-INSPIRED MAGNETIC BEADS FOR ISOLATION OF SPERM FROM HETEROGENOUS SAMPLES IN FORENSIC APPLICATIONS
Forensic Science International: Genetics · 2021 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ MERVE GÖKŞİN KARAASLAN TUNÇ →

Makale Bilgileri

DergiForensic Science International Genetics
Yayın TarihiMayıs 2021
Cilt / Sayfa52
DOI10.1016/j.fsigen.2020.102451
Scopus ID2-s2.0-85100382923
Özet Rapid and efficient processing of sexual assault evidence will accelerate forensic investigation and decrease casework backlogs. The standardized protocols currently used in forensic laboratories require the continued innovation to handle the increasing number and complexity of samples being submitted to forensic labs. Here, we present a new technique leveraging the integration of a bio-inspired oligosaccharide (i.e., Sialyl-LewisX) with magnetic beads that provides a rapid, inexpensive, and easy-to-use strategy that can potentially be adapted with current differential extraction practice in forensics labs. This platform (i) selectively captures sperm; (ii) is sensitive within the forensic cut-off; (iii) provides a cost effective solution that can be automated with existing laboratory platforms; and (iv) handles small volumes of sample (∼200 μL). This strategy can rapidly isolate sperm within 25 minutes of total processing that will prepare the extracted sample for downstream forensic analysis and ultimately help accelerate forensic investigation and reduce casework backlogs.

Yazarlar (9)

1
Fatih Inci
2
Merve Gökşin Karaaslan
3
Rakhi Gupta
4
Anirudh Avadhani
5
Mehmet Giray Ogut
6
Ekin Erin Atila
7
George Duncan
ORCID: 0000-0002-4931-5316
8
Leonard Klevan
ORCID: 0000-0003-3708-7181
9
Utkan Demirci

Anahtar Kelimeler

Bio-inspired material Cell separation Forensics Magnetic beads Sialyl-Lewis X

Kurumlar

DxNow, Inc.
Gaithersburg United States
Nova Southeastern University
Fort Lauderdale United States
Stanford University School of Medicine
Stanford United States

Metrikler

13
Atıf
9
Yazar
5
Anahtar Kelime

Sistemimizdeki Yazarlar

MK
MERVE GÖKŞİN KARAASLAN TUNÇ
DOKTOR ÖĞRETİM ÜYESİ

Hızlı Erişim

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