Scopus
YÖKSİS Eşleşti
Characterization of the antioxidant activity, total phenolic content, enzyme inhibition, and anticancer properties of Achillea millefolium L. (yarrow)
Instrumentation Science and Technology · Ocak 2022
YÖKSİS Kayıtları
Characterization of the antioxidant activity, total phenolic content, enzyme inhibition, and anticancer properties of Achillea millefolium L. (yarrow)
INSTRUMENTATION SCIENCE & TECHNOLOGY · 2022 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ MERVE GÖKŞİN KARAASLAN TUNÇ →
Makale Bilgileri
DergiInstrumentation Science and Technology
Yayın TarihiOcak 2022
Cilt / Sayfa50 · 654-667
Scopus ID2-s2.0-85130588426
Özet
The antioxidant activity, total phenolic content, enzyme inhibition, anticancer properties of Achillea millefolium L. (yarrow), which is generally consumed by humans as herbal tea, were investigated. Yarrow extracts were prepared with different extraction techniques and solvents and the optimum conditions were determined. When the antioxidant activity and total phenolic content results were evaluated, the best yield was obtained with ultrasound-assisted extraction for all solvents. Moreover, the yields from highest to lowest were methanol, water, and acetonitrile. The enzyme inhibition and anticancer of Achillea millefolium L. extracts using methanol were evaluated. The IC50 values for the inhibition of xanthine oxidase and acetylcholinesterase were 4.974 ± 0.54 and 21.891 ± 1.118 µg/mL, respectively. The extract concentration was determined to be 23.85 μg/mL for 50% reduction in growth inhibitory activity cell viability (IC50) against breast cancer (MCF-7).
Yazarlar (5)
1
Nagihan Karaaslan Ayhan
ORCID: 0000-0001-9083-9149
2
Merve Goksin Karaaslan-Tunc
ORCID: 0000-0003-2645-808X
3
Samir Abbas Ali Noma
ORCID: 0000-0003-4165-0045
4
Ali Kurucay
ORCID: 0000-0002-8816-0425
5
Burhan Ates
ORCID: 0000-0001-6080-229X
Anahtar Kelimeler
Achillea millefoliumL
anticancer
antioxidant
extraction
inhibition
Kurumlar
Bursa Uludağ Üniversitesi
Bursa Turkey
Inönü Üniversitesi
Malatya Turkey
Munzur University
Tunceli Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
4
Atıf
5
Yazar
5
Anahtar Kelime