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Role of Rhipicephalus bursa larvae in transstadial transmission and endemicity of Babesia ovis in chronically infected sheep

Frontiers in Cellular and Infection Microbiology · Ocak 2024

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YÖKSİS Kayıtları
Role of Rhipicephalus bursa larvae in transstadial transmission and endemicity of Babesia ovis in chronically infected sheep
Frontiers in Cellular and Infection Microbiology · 2024 SCI-Expanded
DOÇENT ONUR CEYLAN →
Role of Rhipicephalus bursa larvae in transstadial transmission and endemicity of Babesia ovis in chronically infected sheep
Frontiers in Cellular and Infection Microbiology · 2024 SCI-Expanded
PROFESÖR FERDA SEVİNÇ →

Makale Bilgileri

DergiFrontiers in Cellular and Infection Microbiology
Yayın TarihiOcak 2024
Cilt / Sayfa14
Erişim🔓 Açık Erişim
Özet Babesia ovis, transmitted by Rhipicephalus bursa ticks, is the causative agent of ovine babesiosis, a disease characterized by fever, anemia, hemoglobinuria, and high mortality in sheep. This study investigates whether sheep that survived babesiosis without treatment can serve as a source of infection for B. ovis-free host-seeking R. bursa larvae in a later season. Three donor sheep were experimentally infected with B. ovis, and after six months, persistence of B. ovis was assessed through blood and tick transmission experiments. Blood from donor sheep was intravenously injected into three recipient sheep, while donor sheep were also infested with B. ovis-free R. bursa larvae. Engorged nymphs molted to adults, and new recipient sheep were infested with these ticks. All recipient sheep were monitored for B. ovis for 100 days using microscopic, serological, and molecular approaches. The presence of B. ovis was confirmed in the recipient sheep that received blood, leading to clinical infection in two. However, no B. ovis was detected in recipient sheep infested with ticks. These results suggest that sheep recovering from B. ovis infection do not serve as a source of infection for R. bursa larvae in subsequent seasons.

Yazarlar (8)

1
Recep Firat
2
Mehmet Can Ulucesme
ORCID: 0000-0002-4492-143X
3
Munir Aktas
ORCID: 0000-0002-3188-8757
4
Onur Ceylan
5
Ferda Sevinc
6
Reginaldo G. Bastos
7
Carlos E. Suarez
8
Sezayi Ozubek

Anahtar Kelimeler

Babesia ovis ELISA experimental infection PCR Rhipicephalus bursa sheep

Kurumlar

Firat Üniversitesi
Elazig Turkey
Selçuk Üniversitesi
Selçuklu Turkey
USDA Agricultural Research Service
Washington, D.C. United States
Washington State University Pullman
Pullman United States