Scopus
YÖKSİS DOI Eşleşti
SJR Q1
Effectiveness of melatonin on aflatoxicosis in chicks
Research in Veterinary Science · Haziran 2009
YÖKSİS Kayıtları
Effectiveness of melatonin on aflatoxicosis in chicks
Research in Veterinary Science · 2009 SCI-Expanded
Prof. Dr. MEHMET TUZCU →
Effectiveness of melatonin on aflatoxicosis in chicks
Research in Veterinary Science · 2009 SCI
Prof. Dr. MEHMET TUZCU →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Effects of boron supplementation of adequate and inadequate vitamin D3 containing diet on performance and serum biochemical characters of broiler chickens
2001 ISSN: 00345288 SCI
Prof. Dr. FİRUZE KURTOĞLU →
Evaluation of biochemical characters of broiler chickens during dietary aflatoxin 50 and 100ppb and clinoptilolite exposure
2002 ISSN: 00345288 SCI
Prof. Dr. FİRUZE KURTOĞLU →
Effect of clinoptilolite on serum biochemical anf haematological characters of broiler chickens duringaflatoxicosis
2000 ISSN: 0034-5288 SCI 91 atıf
Prof. Dr. TUFAN KEÇECİ →
Effects of zinc and vitamin A supplements on plasma levels of thyroid hormones cholesterol glucose and egg yolk cholesterol of laying hens
2001 ISSN: 00345288 SCI 31 atıf
Prof. Dr. TUFAN KEÇECİ →
Effects of hypotaurine cysteamine and aminoacids solution on post thaw microscopic and oxidative stress parameters of Angora goat semen
2009 ISSN: 00345288 SCI-Expanded
Prof. Dr. MUSTAFA NUMAN BUCAK →
Effectiveness of melatonin on aflatoxicosis in chicks
2009 ISSN: 00345288 SCI
Prof. Dr. MEHMET TUZCU →
Effects of hypotaurine cysteamine and aminoacids solution on post thaw microscopic and oxidative stress parameters of Angora goat semen
2009 ISSN: 00345288 SCI-Expanded 3 atıf
Prof. Dr. NURİ BAŞPINAR →
Effect of Tilmicosin on Serum Cytokine Levels in the Endotoxemia
2009 ISSN: 0034-5288 SCI-Expanded 25 atıf
Prof. Dr. MUAMMER ELMAS →
Feeding diets supplemented with zinc and vitamin A in laying hens effects on histopathological findings and tissue mineral contents
2002 ISSN: 0034-5288 SCI-Expanded 1 atıf
Prof. Dr. SEYFULLAH HALİLOĞLU →
The effects of aflatoxin on the reproductive system of roosters
2002 ISSN: 0034-5288 SCI-Expanded
Prof. Dr. MUSTAFA ORTATATLI →
Effects of zinc and vitamin A supplements on plasma levels of thyroid hormones cholesterol glucose and egg yolk cholesterol of laying hens
2001 ISSN: 0034-5288 SCI-Expanded 23 atıf
Prof. Dr. SEYFULLAH HALİLOĞLU →
Pharmacokinetics of enrofloxacin following intravenous and intramuscular administration in Angora rabbits
2007 ISSN: 00345288 SCI-Expanded
Prof. Dr. MUAMMER ELMAS →
Feeding diets supplemented with zinc and vitamin a in laying hens effects on histopathological findings and tissue mineral contents
2002 ISSN: 0034-5288 SCI-Expanded
Prof. Dr. MUSTAFA ORTATATLI →
Ameliorative effects of dietary clinoptilolite on pathological changes in broiler chickens during aflatoxicosis
2001 ISSN: 0034-5288 SCI-Expanded
Prof. Dr. HALİS UĞUZ →
Effect of clinoptilolite on serum biochemical and haematological characters of broiler chickens during Aflatoxicosis
2000 ISSN: 0034-5288 SCI-Expanded
Prof. Dr. HALİS UĞUZ →
Evaluation of biochemical characters of broiler chickens during dietary aflatoxin 50 and 100
2002 ISSN: 0034-5288 SCI-Expanded
Prof. Dr. HALİS UĞUZ →
Evaluation of pathological changes in broilers during chronic aflatoxin 50 and 100 ppb and clinoptilolite exposure
2005 ISSN: 0034-5288 SCI-Expanded
Prof. Dr. HALİS UĞUZ →
Biological suppression of aflatoxicosis in japanese quail Coturnix coturnix japonica by dietary addition of yeast S cerevisiae
2001 ISSN: 0034-5288 SSCI
Prof. Dr. HALİS UĞUZ →
Preventive efficacy of clinoptilolite in broilers during chronic aflatoxin 50 and 100 ppb Exposure
2000 ISSN: 0034-5288 SCI-Expanded
Prof. Dr. HALİS UĞUZ →
Influence of methiionine and dithioerythritol on sperm motility lipidperoxidation and antioxidant capacities during liquid storage of ramsemen
2010 ISSN: 0034-5288 SCI-Expanded
Prof. Dr. NURİ BAŞPINAR →
Makale Bilgileri
ISSN00345288
Yayın TarihiHaziran 2009
Cilt / Sayfa86 · 485-489
Scopus ID2-s2.0-64449083050
Özet
The efficacy of melatonin co-administration on aflatoxicosis in chicks was investigated. Ross PM3 breed chicks were divided into groups of 10 and given conventional feed. One of the groups was kept as a control (C), and the others were given 150 ppb aflatoxin (AF1), 300 ppb aflatoxin (AF2), 150 ppb aflatoxin plus 10 mg/kg/bwt melatonin (AF1+M), 300 ppb aflatoxin plus 10 mg/kg/bwt melatonin (AF2+M), 10 mg/kg/bwt melatonin (M), and 1% ethanol (E). After 21 day-treatment period, the chicks were sacrificed, liver and kidney tissues were collected, processed for immuno-histochemical staining, in situ TUNEL method, and biochemical analyses. Vacuolar degeneration, necrosis, bile duct hyperplasia in liver, and mild tubular degeneration in kidney were detected in AF groups. Pathological changes were markedly reduced in AF+M groups, and a microscopic view similar to group C was observed. Increased immunoreactivity against inducible nitric oxide synthase (iNOS) and nitrotyrosine was detected in AF groups compared to weak immunoreactivity in group C. Immunoreactivity in AF+M groups was markedly reduced compared to AF groups and was similar to group C in liver and kidney. Many apoptotic cells were detected in the livers of AF groups, whereas there were no apoptotic cells in AF+M groups. While reduced glutathione (GSH) levels in liver and kidney of AF groups were greatly reduced, malondialdehyde (MDA) levels increased. With melatonin co-administration, the levels of GSH and MDA approached to the values of group C. These results indicated that nitrosative tissue degeneration caused by aflatoxin could be greatly reduced by melatonin supplementation in chicks. © 2008 Elsevier Ltd. All rights reserved.
Yazarlar (6)
1
H. Özen
2
M. Karaman
3
Y. ÇiǧremIs
4
Mehmet Tuzcu
5
K. Özcan
6
Dinçer Erdaǧ
Anahtar Kelimeler
Aflatoxin
Apoptosis
GSH
iNOS
MDA
Melatonin
Nitrotyrosine
Kurumlar
Kafkas Üniversitesi
Kars Turkey
Kafkas Üniversitesi, Veteriner Fakültesi
Kars Turkey
Veterinary Control and Research Institute
Adana Turkey
Scimago Dergi (ISSN Eşleşmesi)
Research in Veterinary Science
Q1
SJR Skoru0,537
H-Index100
YayıncıElsevier B.V.
ÜlkeNetherlands
Veterinary (miscellaneous) (Q1)
Metrikler
40
Atıf
6
Yazar
7
Anahtar Kelime