Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q2
Strontium chloride: Can it be a new treatment option for ulcerative colitis?
Biomed Research International · Ocak 2014
YÖKSİS Kayıtları
Strontium Chloride: Can It Be a New Treatment Option for Ulcerative Colitis?
Hindawi Limited · 2014 SCI-Expanded
Prof. Dr. MEHMET TUZCU →
YÖKSİS Kayıtları — ISSN Eşleşmesi
The Frequency of Autoimmune Thyroid Disease in Alopecia Areata and Vitiligo Patients
2015 ISSN: 2314-6133 SCI-Expanded
Prof. Dr. GÜLCAN SAYLAM KURTİPEK →
A Comparative Study for the Evaluation of Two Doses of Ellagic Acid on Hepatic Drug Metabolizing and Antioxidant Enzymes in the Rat
2013 ISSN: 2314-6133 SCI-Expanded 12 atıf
Prof. Dr. SERDAR KARAKURT →
The Increase of Intra-Abdominal Pressure Can Affect Intraocular Pressure
2015 ISSN: 2314-6133 SCI-Expanded
Prof. Dr. İLHAN ECE →
Strontium Chloride Can It Be a New TreatmentOption for Ulcerative Colitis
2014 ISSN: 2314-6133 SCI-Expanded
Doç. Dr. NEVİN TUZCU →
Serum Biochemistry of Lumpy Skin Disease Virus Infected Cattle
2016 ISSN: 2314-6133 SCI-Expanded
Prof. Dr. OĞUZHAN AVCI →
Genetic diversity of eight domestic goat populationraised in Turkey
2016 ISSN: 2314-6133 SSCI
Prof. Dr. VAHDETTİN ALTUNOK →
Intrapulpal Thermal Changes during Setting Reaction of Glass Carbomer Using Thermocure Lamp
2016 ISSN: 2314-6133 SCI-Expanded
Prof. Dr. GÜL TOSUN →
Intrapulpal Thermal Changes during Setting Reaction of Glass Carbomer Using Thermocure Lamp
2016 ISSN: 2314-6133 SCI-Expanded
Prof. Dr. HAYRİYE ESRA ÜLKER →
Intrapulpal Thermal Changes during Setting Reaction of Glass Carbomer® Using Thermocure Lamp
2016 ISSN: 2314-6133 SCI-Expanded Q2
Doç. Dr. FİRDEVS KAHVECİOĞLU →
Cytotoxicity Testing of Temporary Luting Cements with Two and Three Dimensional Cultures of Bovine Dental Pulp Derived Cells
2013 ISSN: 2314-6133 SCI-Expanded
Prof. Dr. HAYRİYE ESRA ÜLKER →
Effects of 16 Carbamide Peroxide Bleaching on the Surface Properties of Glazed Glassy Matrix Ceramics
2020 ISSN: 2314-6133 SCI-Expanded
Prof. Dr. NECLA DEMİR →
Real-Time Analysis of Antiproliferative Effects of Mouthwashes Containing Alcohol, Sodium Fluoride, Cetylpyridinium Chloride, and Chlorhexidine In Vitro
2021 ISSN: 2314-6133 SCI-Expanded Q2
Doç. Dr. FİRDEVS KAHVECİOĞLU →
Real-Time Analysis of Antiproliferative Effects of Mouthwashes Containing Alcohol, Sodium Fluoride, Cetylpyridinium Chloride, and Chlorhexidine In Vitro
2021 ISSN: 2314-6133 SCI-Expanded Q2
Prof. Dr. HAYRİYE ESRA ÜLKER →
Strontium Chloride: Can It Be a New Treatment Option for Ulcerative Colitis?
2014 ISSN: 2314-6133 SCI-Expanded
Prof. Dr. MEHMET TUZCU →
Bonding Effectiveness of Saliva-Contaminated Monolithic Zirconia Ceramics Using Different Decontamination Protocols
2024 ISSN: 2314-6133 ESCI
Prof. Dr. NECLA DEMİR →
Makale Bilgileri
ISSN23146133
Yayın TarihiOcak 2014
Cilt / Sayfa2014
Scopus ID2-s2.0-84904101659
Erişim🔓 Açık Erişim
Özet
Background/Aims. Patients with ulcerative colitis still need effective therapy without major side effects. It has been found that strontium can suppress NFκB activation induced by TNF-α. This opens a gate to a new anti-TNF agent which is cheap and can be given orally. We for the first time aimed to investigate the effect of strontium chloride (SrCl on inflammation in experimental colitis. Methods. Thirty female Wistar albino rats were divided into 5 groups each containing 6 rats. The rats in groups 1 and 2 served as the healthy control and colitis group, respectively. The rats in groups 3, 4, and 5 had colitis and received 40 mg/kg SrCl 160 mg/kg SrCl<2<, and 1 mg/kg prednisolone by oral gavage, respectively. The rats were sacrificed for histological evaluation and determination of serum neopterin, TNF-α, and IFN-γ levels. Results. The neopterin, TNF-α and IFNγ levels of group 2 was significantly higher than the other groups. The neopterin, TNF-α, and IFN-γ levels of controls and other treatment groups were comparable. There were a significant difference in macroscopic and microscopic healing between group 2 and other groups histologically. But there was not a significant difference within treatment receiving groups. Conclusion. SrClhad comparable therapeutic efficiency with prednisolone. © 2014 Firdevs Topal et al.
Yazarlar (6)
1
Firdevs Topal
2
Ozlem Yonem
3
Nevin Tuzcu
ORCID: 0000-0001-5899-3955
4
Mehmet Tuzcu
5
Hilmi Ataseven
6
Melih Akyol
Kurumlar
Anadolu Hospital
Sivas Turkey
Ataturk Training and Research Hospital
Izmir Turkey
Cumhuriyet Üniversitesi
Sivas Turkey
Scimago Dergi (ISSN Eşleşmesi)
BioMed Research International
Q2
OA
SJR Skoru0,748
H-Index219
YayıncıJohn Wiley and Sons Ltd
ÜlkeUnited Kingdom
Biochemistry, Genetics and Molecular Biology (miscellaneous) (Q2)
Immunology and Microbiology (miscellaneous) (Q2)
Medicine (miscellaneous) (Q2)
Metrikler
9
Atıf
6
Yazar