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Scopus 🔓 Açık Erişim YÖKSİS DOI Eşleşti SJR Q4

Evaluation of tumor necrosis Factor Alpha, Interferon Gamma, Procalcitonin and Neopterin levels in Brucella seropositive cattle

Revista Cientifica De La Facultad De Veterinaria · Ocak 2023

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YÖKSİS Kayıtları
Evaluation of tumor necrosis Factor Alpha, Interferon Gamma, Procalcitonin and Neopterin levels in Brucella seropositive cattle
Universidad del Zulia · 2023 SCI-Expanded
Doç. Dr. NEVİN TUZCU →
Evaluation of tumor necrosis Factor Alpha, Interferon Gamma, Procalcitonin and Neopterin levels in Brucella seropositive cattle
Universidad del Zulia · 2023 SCI-Expanded
Prof. Dr. MEHMET TUZCU →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 20 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
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Effect of Tarantula cubensis alcoholic extract and Nerium oleander distillate on cell proliferation markers in colon carcinogenesis
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Investigation with Real-Time PCR and Histopathology on the presence of H. felis, H. heilmannii and H. pylori in dogs
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Investigation with Real-Time PCR and Histopathology on the presence of H. felis, H. heilmannii and H. pylori in dogs
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Determination of Embryotoxic effects of Atipamezole using in ovo model
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Evaluation of tumor necrosis Factor Alpha, Interferon Gamma, Procalcitonin and Neopterin levels in Brucella seropositive cattle
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ELISA-based Point Prevalence of enteropathogens in diarrheic calves in Central Anatolia Region of Turkey
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Effect of Tarantula cubensis alcohol extract and Capecitabin combine in Colorectal Cancer rats
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Determination of the embryotoxic effect of Metronidazole using an in ovo model
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ELISA–based Point Prevalence of enteropathogens in diarrheic calves in Central Anatolia Region of Turkey
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ELISA-based Point Prevalence of enteropathogens in diarrheic calves in Central Anatolia Region of Turkey
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Microbiological characterization and genetic analysis of bacteria isolated from blood cultures and fecal samples in calves with symptoms of septicemia and diarrhea
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Microbiological characterization and genetic analysis of bacteria isolated from blood cultures and fecal samples in calves with symptoms of septicemia and diarrhea
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Microbiological characterization and genetic analysis of bacteria isolated from blood cultures and fecal samples in calves with symptoms of septicemia and diarrhea
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Pathological and biochemical investigation of the effects of Silybum marianum against Methomyl damage in broiler liver
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Makale Bilgileri

ISSN07982259
Yayın TarihiOcak 2023
Cilt / Sayfa33
Erişim🔓 Açık Erişim
Özet Brucellosis is a zoonotic disease that affects a large number of people and animals, causing physical disability, workforce loss and significant economic losses in the livestock industry. In the current study, it was aimed to determine and compare the levels of tumor necrosis factor alpha (TNF–α), interferon gamma (IFN–γ), Procalcitonin (PCT) and Neopterin in the blood serums of cattle with brucellosis and vaccinated against brucellosis. The materials of this study consisted of a total 48 blood serums belonging to three basic groups, each consisting of 16 animals. Disease group (1st group) were divided into two subgrups each consisting of 8 animals that 21st day after abortion and seropositive 7 months pregnant, the vaccinated (2nd group) and the control (3rd group) groups were divided into two subgroups, each consisting of 8 animals that gave birth 21 days ago and 7 months pregnant. IFN–γ and PCT levels were determined by sandwich enzyme immunoassay, TNF–α and Neopterin levels were determined using competitive inhibition enzyme immunoassay method by using ELISA device. In this study, TNF–α, PCT and Neopterin levels measured in the blood serums of the Brucella seropositive (1st), conjunctival Brucella abortus S19 vaccine administered (2nd) and unvaccinated Brucella seronegative control groups were compared and no significant difference could be determined between the subgroups of the groups (P>0.05). There were a significant differences between 1st, 2nd, and 3rd groups (P<0.05). IFN–γ levels determined in the blood serums of 1st, 2nd and 3rd groups were compared and nosignificant differences were found between the subgroups of 2nd and 3rd groups (P>0.05), but there were a significant differences between the subgroups of the 1st group (P<0.05). Similarly, a significant differences were determined between 1st, 2nd and 3rd groups in terms of IFN–γ levels (P<0.05). As a result, it was thought that detecting very high serum TNF–α, IFN–γ, neopterin levels in cattle with brucellosis would be helpful in the diagnosis and follow–up of brucellosis. However, it was concluded that there is a need for controlled studies comparing more herds with brucellosis to determine whether the relevant cytokines can be used in the diagnosis of brucellosis.

Yazarlar (3)

1
Nevin Tuzcu
ORCID: 0000-0001-5899-3955
2
Mehmet Tuzcu
3
G. Akcakavak

Anahtar Kelimeler

Brucellosis interferon gamma neopterin procalcitonin tumor necrosis factor alpha

Kurumlar

Bozok Üniversitesi
Yozgat Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Revista Cientifica de la Facultad de Veterinaria
Q4 OA
SJR Skoru0,138
H-Index16
YayıncıUniversidad del Zulia, Facultad de Ciencias Veterinarias
ÜlkeVenezuela
Animal Science and Zoology (Q4)
Food Science (Q4)
Immunology and Microbiology (miscellaneous) (Q4)
Veterinary (miscellaneous) (Q4)
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Metrikler

2
Atıf
3
Yazar
5
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