Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Retrospective evaluation of pregnant women with celiac disease
Journal of the Turkish German Gynecology Association · Mart 2017
YÖKSİS Kayıtları
Retrospective evaluation of pregnant women with celiac disease
Journal of the Turkish-German Gynecological Association · 2017 emerging sources citation index
PROFESÖR GÖKÇEN ÖRGÜL →
Makale Bilgileri
DergiJournal of the Turkish German Gynecology Association
Yayın TarihiMart 2017
Cilt / Sayfa18 · 56-59
Scopus ID2-s2.0-85016049259
Erişim🔓 Açık Erişim
Özet
Objective: To show celiac disease (CD) and its poor pregnancy outcome relationship, and to demonstrate the importance of a gluten-free diet together with low-dose low-molecular-weight heparin (LMWH) and low-dose corticosteroid (LDC) in the management of pregnancies with CD. Material and Methods: This study consisted of 2 groups of patients. Six patients with CD (control group) on a gluten-free diet were monitored during their first pregnancies within the framework of antenatal care program and their pregnancy outcomes were compared with eight poorlytreated pregnant patients with CD (study group) who were referred from other medical institutions. LMWH (enoxaparine 1x2000 Anti-XA IU/0.2 mL/day), and LDC (methylprednisolone 1x4 mg p.o/day) were used in the control group. Their obstetric histories and outcomes of their last pregnancies were compared. The patients’ obstetric risk levels were evaluated using the “Beksac Obstetrics Index” (BOI). Results: There were miscarriages in 50% of the study group. There were also 50% and 75% preterm deliveries in the control and study groups, respectively. The BOI of the study group was significantly worse than the control group (1.31 vs. 0.31±0.21, p<0.01). There were no statistically significant differences between age (24±4.7 vs 31.7±6 years, p=0.448), gestational day of birth (259.3±8.5 vs 246.6±24.3), birthweight (2691±698 vs 2262±359 g, p=0.394), and cesarean section rates (p=0.118). Conclusion: CD is a risk factor for adverse pregnancy outcome. Miscarriage and preterm labor are critical complications in pregnancies complicated by CD. A gluten-free diet is important in the treatment. LMWH and LDC seem to be helpful in the management of pregnant women with CD.
Yazarlar (6)
1
Kemal Beksaç
ORCID: 0000-0002-6339-505X
2
Gökçen Örgül
ORCID: 0000-0003-0578-4230
3
Murat Çağan
4
Ahmet Ergun Karaaǧaoǧlu
5
Serap Arslan
6
Mehmet Sinan Beksaç
ORCID: 0000-0001-6362-787X
Anahtar Kelimeler
Celiac disease
Gluten-free diet
Low-dose corticosteroids
Low-molecular- weight heparin
Perinatal morbidity
Pregnancy
Kurumlar
Ankara Oncology Hospital
Ankara Turkey
Hacettepe Üniversitesi
Ankara Turkey
Metrikler
26
Atıf
6
Yazar
6
Anahtar Kelime