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First trimester complete blood cell indices in early and late onset preeclampsia

Turkish Journal of Obstetrics and Gynecology · Haziran 2019

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YÖKSİS Kayıtları
First trimester complete blood cell indices in early and late onset preeclampsia
Turkish Journal of Obstetrics and Gynecology · 2019 ESCI
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Makale Bilgileri

DergiTurkish Journal of Obstetrics and Gynecology
Yayın TarihiHaziran 2019
Cilt / Sayfa16 · 112-117
Erişim🔓 Açık Erişim
Özet Objective: This study aimed to compare the first trimester complete blood count (CBC) indices of pregnancies complicated by early-onset preeclampsia (EOPE) or late-onset preeclampsia (LOPE). Material and Methods: A retrospective case-control study was conducted with 186 patients. Patients were classified into three subgroups: EOPE, LOPE, and control groups. First trimester CBC results were obtained for each patient. Hemoglobin, hematocrit, red blood cell distribution width, mean corpuscular volume, white blood cell (WBC) count, neutrophil, eosinophil, basophil, lymphocyte, monocyte, mean platelet volume, platelet distribution width, plateletcrit, and platelet count were compared. The neutrophil lymphocyte ratio was calculated by dividing the absolute lymphocyte count by the absolute neutrophil count. The platelet lymphocyte ratio was calculated by dividing the absolute lymphocyte count by the absolute platelet count. Results: The total number of cases was 21, 42, and 123, in the EOPE, LOPE, and control groups, respectively. There were statistically significant differences in the total WBC and neutrophil counts between the three groups (both p<0.05). WBC and neutrophil counts were found to be highest in the EOPE group, and the LOPE group had higher levels compared with controls. The optimal cut-off values to predict EOPE for WBC and neutrophil counts were 9.55×103/ µL (sensitivity 71.4% and specificity 70.7%) and 6.45×103/µL (sensitivity 66.7% and specificity 74.8%), respectively. Conclusion: Increased first trimester WBC and neutrophil counts may be predictive for EOPE.

Yazarlar (6)

1
Gökçen Örgül
ORCID: 0000-0003-0578-4230
2
Duygu Aydın Haklı
3
Gonca Ozten
4
Erdem Fadiloglu
5
Atakan Tanacan
ORCID: 0000-0001-8209-8248
6
Mehmet Sinan Beksaç
ORCID: 0000-0001-6362-787X

Anahtar Kelimeler

Complete blood count Early onset preeclampsia Late onset preeclampsia Neutrophil count White blood cell count

Kurumlar

Hacettepe Üniversitesi
Ankara Turkey

Metrikler

40
Atıf
6
Yazar
5
Anahtar Kelime

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