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Is ProBNP a New Marker for Predicting Intrauterine Growth Restriction?

Zeitschrift Fur Geburtshilfe Und Neonatologie · Nisan 2021

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YÖKSİS Kayıtları
Is ProBNP a New Marker for Predicting Intrauterine Growth Restriction?
Zeitschrift für Geburtshilfe und Neonatologie · 2021 SCI-Expanded
Prof. Dr. GÖKÇEN ÖRGÜL →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 4 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
Metabolic Infrastructure of Pregnant Women With Trisomy 21 Fetuses Metabolomic Analysis
2019 ISSN: 0948-2393 SCI-Expanded
Prof. Dr. GÖKÇEN ÖRGÜL →
Concerns of Pregnant Women in “Prenatal Screening/Diagnosis” Practice and Termination of Pregnancy
2020 ISSN: 0948-2393 SCI-Expanded
Prof. Dr. GÖKÇEN ÖRGÜL →
Is ProBNP a New Marker for Predicting Intrauterine Growth Restriction?
2021 ISSN: 0948-2393 SCI-Expanded Q4
Prof. Dr. GÖKÇEN ÖRGÜL →
Effectiveness of Moxibustion for Breech Presentation: A Prospective Study
2022 ISSN: 0948-2393 SCI-Expanded Q4
Prof. Dr. GÖKÇEN ÖRGÜL →

Makale Bilgileri

ISSN09482393
Yayın TarihiNisan 2021
Cilt / Sayfa225 · 125-128
Özet Purpose To evaluate the usability of first-trimester maternal serum ProBNP levels in the prediction of intrauterine growth restriction (IUGR). Methods In this prospective study, blood samples taken from 500 women who applied to our polyclinic for routine serum aneuploidy screening between the 11-14th gestational weeks were centrifuged. The obtained plasma samples were placed in Eppendorf tubes and stored at -80+°C. For the final analysis, first-trimester maternal serum ProBNP levels of 32 women diagnosed with postpartum IUGR and 32 healthy women randomly selected as the control group were compared. FGR was defined as estimated fetal weight below the 10th percentile for the gestational age. Results The mean ProBNP levels were statistically and significantly higher in the women with intrauterine growth restriction (113.73±94.69 vs. 58.33±47.70 pg/mL, p<0.01). At a cut-off level of 50.93, ProBNP accurately predicted occurrence of IUGR (AUC+= 0.794 (95% confidence interval 0.679-0.910), p+= 0.001) with sensitivity and specificity rates of 78.1 and 69.0%, respectively. Conclusion First-trimester serum ProBNP level was significantly higher in women who developed IUGR compared to healthy controls. First-trimester ProBNP level can be used as a potential marker to predict the development of IUGR in pregnant women.

Yazarlar (7)

1
Hasan Eroğlu
ORCID: 0000-0002-1180-5299
2
Nazan Vanll Tonyall
3
Gökçen Örgül
ORCID: 0000-0003-0578-4230
4
Derya Biriken
ORCID: 0000-0002-6254-4578
5
Aykan Yücel
6
Nuray Yazihan
ORCID: 0000-0003-1237-8468
7
Dilek Uygur

Anahtar Kelimeler

first trimester intrauterine growth restriction placenta Pregnancy ProBNP

Kurumlar

Ankara Üniversitesi
Ankara Turkey
Etlik Zubeyde Hanim Women's Health Education and Research Hospital
Ankara Turkey
Scimago Dergi (ISSN Eşleşmesi)
Zeitschrift fur Geburtshilfe und Neonatologie
Q3
SJR Skoru0,264
H-Index22
YayıncıGeorg Thieme Verlag
ÜlkeGermany
Maternity and Midwifery (Q3)
Medicine (miscellaneous) (Q3)
Obstetrics and Gynecology (Q3)
Pediatrics, Perinatology and Child Health (Q3)
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