Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Etiology and perinatal outcomes between early and late-onset nonimmune hydrops fetalis
Revista da Associacao Medica Brasileira · Ocak 2024
YÖKSİS Kayıtları
Etiology and perinatal outcomes between early and late-onset nonimmune hydrops fetalis
Revista da Associação Médica Brasileira · 2024 SCI-Expanded
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Makale Bilgileri
DergiRevista da Associacao Medica Brasileira
Yayın TarihiOcak 2024
Cilt / Sayfa70
Scopus ID2-s2.0-85199325011
Erişim🔓 Açık Erişim
Özet
OBJECTIVE: We aimed to compare the etiology and perinatal outcomes of non-immune hydrops fetalis diagnosed early- and late-onset at our hospital. METHODS: The records of the patients who applied to our department were reviewed, and we reached 42 non-immune hydrops fetalis cases retrospectively and examined the medical records. Hydrops diagnosis week, birth week, accompanying anomalies, and perinatal outcomes were compared as ≤12 weeks (early-onset) and >12 weeks (late-onset). RESULTS: The prevalence of non-immune hydrops fetalis was 0.05%, and the median week of diagnosis for hydrops was 18 weeks. Consanguinity (16.7%) was found in seven pregnancies, and the other seven patients (16.7%) had a history of hydrops in previous pregnancies. Anomalies of the skeletal system, central nervous system, and gastrointestinal tract accounted for 66.7% of ≤12 weeks in non-immune hydrops fetalis cases. Cardiac abnormalities were more common (26.7%) in patients at > 12 weeks (p=0.078). A statistically significant difference was found between the distribution of week of birth and week of diagnosis (p=0.029). Notably, 66.7% of patients diagnosed before week 12 and 23.3% of patients diagnosed after week 12 delivered their babies before week 24. Spontaneous intrauterine death occurred before week 12 in 45.5% (n=5) of nonimmune hydrops fetalis and after week 12 in 39.1% (n=9) of non-immune hydrops fetalis. Notably, 69.2% (n=9) of the patients who had prenatal invasive testing resulted in normal karyotype. CONCLUSION: In this study, most of the fetuses diagnosed with early-onset non-immune hydrops fetalis were born in the first 24 weeks. Additionally, live birth rates and cardiac anomalies were observed to be higher in late-onset non-immune hydrops fetalis.
Yazarlar (8)
1
Seval Yılmaz Ergani
ORCID: 0000-0002-7017-8854
2
Müjde Can İbanoğlu
ORCID: 0000-0002-8413-2064
3
Ayberk Çakır
ORCID: 0000-0001-5749-4556
4
Çağlayan Ateş
ORCID: 0000-0002-4200-2659
5
Gökçen Örgül
ORCID: 0000-0003-0578-4230
6
Nazan Vanlı Tonyalı
ORCID: 0000-0002-7284-6887
7
Özge Yücel Çelik
ORCID: 0000-0002-7746-1943
8
Dilek Şahin
ORCID: 0000-0001-8567-9048
Anahtar Kelimeler
Cardiovascular abnormalities
Congenital abnormalities
Hydrops fetalis
Non-immune hydrops fetalis
Kurumlar
Etlik Zubeyde Hanim Women's Health Training and Research Hospital
Ankara Turkey