Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q4
Effects of herbal-based toothpastes on cell viability
Tropical Journal of Pharmaceutical Research · Nisan 2022
YÖKSİS Kayıtları
Effects of herbal-based toothpastes on cell viability
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH · 2022 SCI-Expanded
Prof. Dr. HAYRİYE ESRA ÜLKER →
Effects of herbal-based toothpastes on cell viability
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH · 2022 SCI-Expanded
Doç. Dr. FİRDEVS KAHVECİOĞLU →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Effects of herbal-based toothpastes on cell viability
2022 ISSN: 1596-5996 SCI-Expanded Q3
Doç. Dr. FİRDEVS KAHVECİOĞLU →
Effects of herbal-based toothpastes on cell viability
2022 ISSN: 1596-5996 SCI-Expanded Q3
Prof. Dr. HAYRİYE ESRA ÜLKER →
Effect of high fructose consumption on plasma levels of leptin, adropin and insulin, and serum biochemical parameters in mature adult rats
2022 ISSN: 1596-5996 SCI-Expanded Q4
Prof. Dr. SEYFULLAH HALİLOĞLU →
Tarantula cubensis alcoholic extract enhances the tumoricidal effect of capecitabine via multiple pathways in azoxymethane-induced colorectal cancer in rats
2024 ISSN: 1596-5996 Scopus
Arş. Gör. ZEYNEP ÇELİK KENAR →
Tarantula cubensis alcoholic extract enhances the tumoricidal effect of capecitabine via multiple pathways in azoxymethane-induced colorectal cancer in rats
2024 ISSN: 1596-5996 SCI-Expanded Q4
Prof. Dr. ÖZGÜR ÖZDEMİR →
Makale Bilgileri
ISSN15965996
Yayın TarihiNisan 2022
Cilt / Sayfa21 · 795-799
Scopus ID2-s2.0-85130051240
Erişim🔓 Açık Erişim
Özet
Purpose: To evaluate the effects of herbal-based toothpastes with different contents on the viability of L929 cells. Methods: Herbal-based toothpastes {Aloe vera - propolis herbal toothpaste, Group 1; Parodontax, Group 2; Toothpaste with miswak, propolis and tea tree extract, Group 3, Dent natural protective toothpaste with clay, Group 4; Gano fresh, Group 5} were diluted (1:1, 1:2, 1:4, 1:8, 1:16, and 1:32) in Dulbecco's modified Eagle's medium. L929 fibroblast cells were treated with the medium containing the herbal toothpastes for 2 min. Cell viability was assessed using methyl tetrazolium test. The viability of the negative control group was set at 100 %, and the percentage viability of all groups was determined accordingly. Results: Cell viability was significantly reduced at all dilutions in Group 5 (p = 0.00). This trend was also observed in Group 4. All dilutions except 1:32 significantly affected cell viability (p = 0.00). In Group 2, only the 1:1 dilution showed a toxic effect (p = 0.00). The samples in Groups 1 and 3 did not show statistically significant cytotoxicity to L929 cells (p > 0.05). Conclusion: Herbal toothpastes containing substances such as sodium lauryl sulfate (Group 5) and sodium benzoate (Groups 2 and 4) are cytotoxic towards L929 cells. Groups 1 and 3 did not contain detergents but contain potassium sorbate as a preservative; hence, they are not toxic.
Yazarlar (2)
1
Firdevs Kahvecioğlu
ORCID: 0000-0003-4216-0849
2
H. E. Ülker
Anahtar Kelimeler
Cytotoxicity
Herbal toothpaste
Potassium sorbate
Sodium benzoate
Sodium lauryl sulfate
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Tropical Journal of Pharmaceutical Research
Q4
OA
SJR Skoru0,165
H-Index56
YayıncıUniversity of Benin
ÜlkeNigeria
Pharmaceutical Science (Q4)
Pharmacology (medical) (Q4)