Scopus
YÖKSİS DOI Eşleşti
SJR Q1
The effects of melatonin and colchicine on ischemia–reperfusion injury in experimental rat testicular torsion model
Journal of Pediatric Surgery · Nisan 2017
YÖKSİS Kayıtları
The effects of melatonin and colchicine on ischemia reperfusion injury in experimental rat testicular torsion model
Journal of Pediatric Surgery · 2016 SCI
Prof. Dr. İLHAN ÇİFTCİ →
The effects of melatonin and colchicine on ischemia–reperfusion injury in experimental rat testicular torsion model
Journal of Pediatric Surgery · 2016 SCI
Prof. Dr. TAMER SEKMENLİ →
The effects of melatonin and colchicine on ischemia reperfusion injury in experimental rat testicular torsion model
Journal of Pediatric Surgery · 2016 SCI-Expanded
Prof. Dr. TAMER SEKMENLİ →
The effects of melatonin and colchicine on ischemia–reperfusion injury in experimental rat testicular torsion model
Journal of Pediatric Surgery · 2016 SCI
Doç. Dr. GÜLSÜM ABUŞOĞLU →
The effects of melatonin and colchicine on ischemia reperfusion injury in experimental rat testicular torsion model
Journal of Pediatric Surgery · 2017 SCI
Prof. Dr. BAHADIR ÖZTÜRK →
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Management of postdural puncture headache with epidural saline patch in a 10 year old child after inguinal hernia repair A case report
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Management of postdural puncture headache with epidural saline patch in a 10 year old child after inguinal hernia repair A case report
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The effects of melatonin and colchicine on ischemia reperfusion injury in experimental rat testicular torsion model
2017 ISSN: 00223468 SCI
Prof. Dr. BAHADIR ÖZTÜRK →
The effects of melatonin and colchicine on ischemia reperfusion injury inexperimental rat testicular torsion model
2017 ISSN: 0022-3468 SCI
Prof. Dr. METİN GÜNDÜZ →
The effects of melatonin and colchicine on ischemia–reperfusion injury in experimental rat testicular torsion model
2016 ISSN: 00223468 SCI Q3
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What predicts spontaneous passage of ≤ 1 cm ureteral stones in children?
2020 ISSN: 0022-3468 SCI-Expanded
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The effect of azygos vein preservation on postoperative complications after esophageal atresia repair: Results from the Turkish Esophageal Atresia Registry
2021 ISSN: 0022-3468 SCI-Expanded Q2
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Reply to the letter 'how can we better estimate the spontaneous passage of ≤1 cm ureteral stones in children?'
2021 ISSN: 0022-3468 SCI-Expanded Q2
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The effect of azygos vein preservation on postoperative complications after esophageal atresia repair: Results from the Turkish Esophageal Atresia Registry
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Isolated omental hydatid cyst clinical radiologic and pathologic findings
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Makale Bilgileri
ISSN00223468
Yayın TarihiNisan 2017
Cilt / Sayfa52 · 582-586
Scopus ID2-s2.0-85007311209
Özet
Purpose The aim of the present study is to investigate the efficiency of colchicine and melatonın in an experimental rat testicular torsion model in the light of histological and biochemical data. Methods A total of 34 Wistar albino male rats were randomly divided into 5 groups as: Group C (control, n = 6), Group S (sham; underwent only left scrotal exploration, n = 7), Group TD (torsion and detorsion; 6 h of ischemia and 7 days of reperfusion, n = 7), Group TD/M (TD + Melatonin; 6 h of ischemia and 7 days of reperfusion and 7 days of 17 mg/kg intraperitoneal melatonin per day, n = 7), group TD/Col (TD + Colchicine; 6 h of ischemia and 7 days of reperfusion and 7 days of 1 mg/kg oral colchicine per day, n = 7). Histopathologic evaluation of seminiferous tubule deterioration was performed by Johnsen's scoring system. Total antioxidant status (TAS), total oxidant status (TOS), IL-6, TNF alpha levels were analyzed in each group. Results The histopathologic scores, total antioxidant status (TAS), total oxidant status (TOS), IL-6, TNF alpha levels in groups C and TD/Col were significantly lower than groups TD and TD/M (P < .001). Conclusion Our study results revealed that colchicine reduced testicular ischemia–reperfusion injury in experimental rat testis torsion model. Although detorsion of testis is crucial for the preserving the testicular viability, antioxidant and anti-inflammatory treatment modalities like colchicine might help to reduce ischemia–reperfusion injury in detorsed testis.
Yazarlar (7)
1
Tamer Sekmenli
2
Metin Gündüz
3
Bahadır Öztürk
4
Pınar Karabağlı
ORCID: 0000-0002-5558-0175
5
Ilhan Çiftci
6
G. Tekin
7
Mustafa Yilmaz
Anahtar Kelimeler
Antioxidants
Colchicine
Melatonin
Rat testis
Reperfusion injury
Spermatic cord torsion
Kurumlar
Selçuk Tip Fakültesi
Konya Turkey
Scimago Dergi (ISSN Eşleşmesi)
Journal of Pediatric Surgery
Q1
SJR Skoru0,950
H-Index147
YayıncıW.B. Saunders
ÜlkeUnited States
Medicine (miscellaneous) (Q1)
Pediatrics, Perinatology and Child Health (Q1)
Surgery (Q1)
Metrikler
13
Atıf
7
Yazar
6
Anahtar Kelime