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Scopus 🔓 Açık Erişim YÖKSİS DOI Eşleşti SJR Q3

Effect of static magnetic field with quercetin and hesperetin on MCF-7 and MDA MB-231 breast cancer cells

Turkish Journal of Biochemistry · Aralık 2020

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YÖKSİS Kayıtları
Effect of static magnetic field with quercetin and hesperetin on MCF-7 and MDA MB-231 breast cancer cells
Turkish Journal of Biochemistry-Turk Biyokimya Dergisi · 2020 SCI-Expanded
Prof. Dr. BAHADIR ÖZTÜRK →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 20 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
Asymmetric dimethylarginine and arginine levels in patients with rheumatoid arthritis
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Asymmetric dimethylarginine and arginine levels in patients with rheumatoid arthritis
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Asymmetric dimethylarginine levels in Behçet s Disease
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Asymmetric dimethylarginine and arginine levels in patients with rheumatoid arthritis
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Makale Bilgileri

ISSN02504685
Yayın TarihiAralık 2020
Cilt / Sayfa45 · 833-841
Erişim🔓 Açık Erişim
Özet Objectives: Static magnetic field (SMF) was previously in practice for the therapy of some diseases and it has been thought that it may be a reliable supportive technique. The aim of this study was to find out the synergistic effect of SMF administration with flavonoids in terms of apoptosis on breast cancer cell lines. Material and methods: The effects of flavonoids on the proliferation of breast cancer cell lines were observed by MTT cell viability test. The cells were treated with SMF + hesperetin and SMF + quercetin. Apoptosis rates and Bax, Bcl-2 protein levels were detected by flow cytometer and Western Blot, respectively. Results: Cell lines were treated with quercetin and quercetin + SMF, substantial amount of cells [3.96, 4.86, 11.40% for MCF-7 and MDA MB-231 cell lines, respectively (p<0.001)] were mainly in the apoptotic phase. The apoptosis rates of hesperetin and hesperetin + SMF were 2.53, 6.06, 10.10% (p<0.001) for MCF-7 and MDA MB- 231 cell lines, respectively. Bax:Bcl-2 ratios were significantly increased after flavonoids + SMF exposure (2.7 vs. 1.6 fold (p<0.0001) in hesperetin + SMF group and 1.8 vs. 1.3-fold (p<0.0001) in quercetin + SMF group for MCF-7 and MDA MB-231 cell lines, respectively. Conclusions: SMF might support the anti-cancer properties of flavonoids, on breast cancer cells via mitochondriarelated apoptosis pathway.

Yazarlar (2)

1
Gulsum Abusoglu
2
Bahadır Öztürk

Anahtar Kelimeler

Apoptosis Flavonoid MCF-7 MDA MB-231 Static magnetic fields

Kurumlar

Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Turkish Journal of Biochemistry
Q3 OA
SJR Skoru0,232
H-Index26
YayıncıWalter de Gruyter GmbH
ÜlkeGermany
Biochemistry (medical) (Q3)
Biochemistry (Q4)
Clinical Biochemistry (Q4)
Molecular Biology (Q4)
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Metrikler

5
Atıf
2
Yazar
5
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