Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Enzymatic debridement in necrotizing pancreatitis
International Surgery · Mayıs 2015
YÖKSİS Kayıtları
Enzymatic Debridement in Necrotizing Pancreatitis
International Surgery · 2015 SCI-Expanded
PROFESÖR HÜSAMETTİN VATANSEV →
Makale Bilgileri
DergiInternational Surgery
Yayın TarihiMayıs 2015
Cilt / Sayfa100 · 897-902
Scopus ID2-s2.0-84974824434
Erişim🔓 Açık Erişim
Özet
Multiple organ failure and pancreatic necrosis are the factors that determine prognosis in acute pancreatitis attacks.We investigated the effects of collagenase on the debridement of experimental pancreatic necrosis. The study covered 4 groups; each group had 10 rats. Group I was the necrotizing pancreatitis group. Group II was the collagenase group with pancreatic loge by isotonic irrigation following necrotizing pancreatitis. Group III was the collagenase group with pancreatic loge following necrotizing pancreatitis. Group IV was the intraperitoneal collagenase group following necrotizing pancreatitis. The progress of the groups was compared hematologically and histopathologically. There was no difference among the groups regarding the levels of leukocyte, hemogram, and urea. The differences in AST levels between Group I and II; and differences in glucose, calcium, LDH, AST, and amylase between Group II and III; between Group II and IV; between Group I and III; and between Group I and IV were statistically significant (P < 0.05). There were statistically significant differences between Group II and III, and Group II and IV regarding edema, acinar necrosis, inflammatory cell infiltration, hemorrhage, and fat necrosis (P < 0.05). In conclusion, the collagenase preparation used in this experimental pancreatitis model was found to be effective in the debridement of pancreatic necrosis.
Yazarlar (5)
1
Murat Çakır
ORCID: 0000-0001-8789-8199
2
Ahmet Tekin
3
Tevfik Kucukkartallar
4
Hüsamettin Vatansev
5
Adil Kartal
Anahtar Kelimeler
Acute pancreatitis
Collagenase
Debridement
Necrose
Kurumlar
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
2
Atıf
5
Yazar
4
Anahtar Kelime