Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
A nationwide multicentre study in Turkey for establishing reference intervals of haematological parameters with novel use of a panel of whole blood
Biochemia Medica · Ocak 2017
YÖKSİS Kayıtları
A nationwide multicentre study in Turkey for establishing reference intervals of haematological parameters with novel use of a panel of whole blood
Biochemia Medica · 2017 SCI-Expanded
PROFESÖR HÜSAMETTİN VATANSEV →
Makale Bilgileri
DergiBiochemia Medica
Yayın TarihiOcak 2017
Cilt / Sayfa27 · 350-377
Scopus ID2-s2.0-85020689126
Erişim🔓 Açık Erişim
Özet
Introduction: A nationwide multicentre study was conducted to establish well-defined reference intervals (RIs) of haematological parameters for the Turkish population in consideration of sources of variation in reference values (RVs). Materials and methods: K2-EDTA whole blood samples (total of 3363) were collected from 12 laboratories. Sera were also collected for measurements of iron, UIBC, TIBC, and ferritin for use in the latent abnormal values exclusion (LAVE) method. The blood samples were analysed within 2 hours in each laboratory using Cell Dyn and Ruby (Abbott), LH780 (Beckman Coulter), or XT-2000i (Sysmex). A panel of freshly prepared blood from 40 healthy volunteers was measured in common to assess any analyser-dependent bias in the measurements. The SD ratio (SDR) based on ANOVA was used to judge the need for partitioning RVs. RIs were computed by the parametric method with/without applying the LAVE method. Results: Analyser-dependent bias was found for basophils (Bas), MCHC, RDW and MPV from the panel test results and thus those RIs were derived for each manufacturer. RIs were determined from all volunteers’ results for WBC, neutrophils, lymphocytes, monocytes, eosinophils, MCV, MCH and platelets. Gender-specific RIs were required for RBC, haemoglobin, haematocrit, iron, UIBC and ferritin. Region-specific RIs were required for RBC, haemoglobin, haematocrit, UIBC, and TIBC. Conclusions: With the novel use of a freshly prepared blood panel, manufacturer-specific RIs’ were derived for Bas, Bas%, MCHC, RDW and MPV. Regional differences in RIs were observed among the 7 regions of Turkey, which may be attributed to nutritional or environmental factors, including altitude.
Yazarlar (29)
1
Yesim Ozarda
2
Kiyoshi Ichihara
3
Ebubekir Bakan
4
Harun Polat
5
Nurinnisa Ozturk
6
Nurcan K. Baygutalp
7
Fatma Taneli
8
Yesim Güvenç
9
Murat Ormen
10
Zubeyde Erbayraktar
11
Nurten Aksoy
12
Hatice Sezen
13
Meltem Demir
14
Gulcin Eskandari
15
Gurbuz Polat
16
Nuriye Mete
17
Hatice Yuksel
18
Hüsamettin Vatansev
19
F. Gün
20
Okhan Akin
21
Ozlem Ceylan
22
Tevfik Noyan
23
Ozgul Gozlukaya
24
Yuksel Aliyazicioglu
25
Sevim Kahraman
26
Melahat Dirican
27
Gul Ozlem Tuncer
28
Shogo Kimura
29
Pinar Eker
Anahtar Kelimeler
Complete blood count
Haematology
Multicentre study
Reference intervals
Turkey
Kurumlar
Ataturk University, Faculty of Medicine
Erzurum Turkey
Bursa Uludağ Üniversitesi
Bursa Turkey
Dicle University, Faculty of Medicine
Diyarbakir Turkey
Dokuz Eylül Üniversitesi
Izmir Turkey
Fatih Sultan Mehmet Hospital
Istanbul Turkey
Harran Üniversitesi
Sanliurfa Turkey
Karadeniz Technical University
Trabzon Turkey
Manisa Celâl Bayar Üniversitesi
Manisa Turkey
Medicalpark Hospital
Antakya Turkey
Mersin Üniversitesi Tip Fakültesi
Mersin Turkey
Ordu Üniversitesi
Ordu Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Yamaguchi University Graduate School of Medicine
Ube Japan
Metrikler
20
Atıf
29
Yazar
5
Anahtar Kelime