Scopus
YÖKSİS Eşleşti
Clinical Utility of Total Oxidative Stress and Total Antioxidant Capacity in Childhood Febrile Neutropenia
Journal of Pediatric Hematology/Oncology · Mayıs 2022
YÖKSİS Kayıtları
Clinical Utility of Total Oxidative Stress and Total Antioxidant Capacity in Childhood Febrile Neutropenia
Journal of pediatric hematology/oncology · 2022 SCI-Expanded
DOÇENT BUKET KARA →
Clinical Utility of Total Oxidative Stress and Total Antioxidant Capacity in Childhood Febrile Neutropenia
Journal of pediatric hematology/oncology · 2022 SCI-Expanded
PROFESÖR YAVUZ KÖKSAL →
Clinical Utility of Total Oxidative Stress and Total Antioxidant Capacity in Childhood Febrile Neutropenia
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY · 1990 SCI-Expanded
PROFESÖR HÜSAMETTİN VATANSEV →
Clinical Utility of Total Oxidative Stress and Total Antioxidant Capacity in Childhood Febrile Neutropenia
Journal of Pediatric Hematology/Oncology · 2022 SCI-Expanded
PROFESÖR HÜSAMETTİN VATANSEV →
Makale Bilgileri
DergiJournal of Pediatric Hematology/Oncology
Yayın TarihiMayıs 2022
Cilt / Sayfa44 · 142-146
Scopus ID2-s2.0-85112798112
Özet
The aim is to determine the oxidative status of children with febrile neutropenia (FEN). Blood samples were collected to determine the total antioxidant capacity (TAC) and total oxidative status (TOS) of healthy children (once) and children with FEN after 0, 48, and 96 hours. Eighteen patients with FEN were evaluated. The baseline TAC level of patients was significantly higher than that of the controls (P<0.0001). The TAC levels of patients with FEN with and without antibiotic modification were higher than those of the controls (P=0.002 and 0.02, respectively). The TAC levels of the patients with FEN with antibiotic modification were lower than those of the patients without antibiotic modification (P=0.0224). The oxidative stress index (OSI), calculated TOS/TAS, value of the children with FEN was lower than that of the controls (P<0.0001). The OSI values of the patients with FEN with and without antibiotic modification were lower than those of the control group (P=0.001 and <0.0001, respectively). The TAC values of the patients with antibiotic modification were higher than those of the patients without antibiotic modification (P=0.02). In conclusion, the oxidative status of the children with FEN was affected, and it can give information about the follow-up of FEN.
Yazarlar (6)
1
Buket Kara
2
Fikret Akyürek
3
Hilal Akbas
4
Kubra Ertan
5
Hüsamettin Vatansev
6
Yavuz Koksal
Anahtar Kelimeler
children
febrile neutropenia
oxidative status
oxidative stress index
total antioxidant capacity
total oxidative status
Kurumlar
Selçuk Tip Fakültesi
Konya Turkey
University of Health Sciences
Istanbul Turkey