Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
An evaluation of matrix metalloproteinase-9 (Mmp-9) and tissue inhibitor metalloprotein-ase-1 (Timp-1) Serum levels and the Mmp-9/Timp-1 Ratio in Covid-19 patients
African Health Sciences · Ocak 2023
YÖKSİS Kayıtları
An evaluation of matrix metalloproteinase-9 (Mmp-9) and tissue inhibitor metalloproteinase-1 (Timp-1) Serum levels and the Mmp-9/Timp-1 Ratio in Covid-19 patients
African Journals Online (AJOL) · 2023 SCI-Expanded
PROFESÖR NAZLIM AKTUĞ DEMİR →
An evaluation of matrix metalloproteinase-9 (Mmp-9) and tissue inhibitor metalloproteinase-1 (Timp-1) Serum levels and the Mmp-9/Timp-1 Ratio in Covid-19 patients
African Journals Online (AJOL) · 2023 SCI-Expanded
PROFESÖR ONUR URAL →
An evaluation of matrix metalloproteinase-9 (Mmp-9) and tissue inhibitor metalloproteinase-
1 (Timp-1) Serum levels and the Mmp-9/Timp-1 Ratio in Covid-19 patients
African Health Sciences · 2023 SCI-Expanded
PROFESÖR UĞUR ARSLAN →
An evaluation of matrix metalloproteinase-9 (Mmp-9) and tissue inhibitor metalloproteinase-1 (Timp-1) Serum levels and the Mmp-9/Timp-1 Ratio in Covid-19 patients
African Journals Online (AJOL) · 2023 SCI-Expanded
DOÇENT HAKAN CEBECİ →
An evaluation of matrix metalloproteinase-9 (Mmp-9) and tissue inhibitor metalloprotein- ase-1 (Timp-1) Serum levels and the Mmp-9/Timp-1 Ratio in Covid-19 patients
AFRICAN HEALTH SCIENCES · 2023 SCI-Expanded
PROFESÖR HÜSAMETTİN VATANSEV →
An evaluation of matrix metalloproteinase-9 (Mmp-9) and tissue inhibitor metalloproteinase-1 (Timp-1) Serum levels and the Mmp-9/Timp-1 Ratio in Covid-19 patients
African Journals Online (AJOL) · 2023 SCI-Expanded
PROFESÖR ŞUA SÜMER →
Makale Bilgileri
DergiAfrican Health Sciences
Yayın TarihiOcak 2023
Cilt / Sayfa23 · 37-43
Scopus ID2-s2.0-85156182991
Erişim🔓 Açık Erişim
Özet
Background: The progression of COVID-19 has different clinical presentations, which raises a number of immunological questions. Objectives: This study aimed to investigate MMP-9 and TIMP-1 levels in patients diagnosed with COVID-19 and whether the MMP-9/TIMP-1 ratio is associated with lung involvement in COVID-19. Methods: This study was conducted with 192 patients and 45 healthy controls. ELISA was used to measure the MMP-9 and TIMP-1. Results: The MMP-9 and TIMP-1 levels of the patients were found to be higher than those of the controls. MMP-9 and TIMP-1 were detected more in patients with lung involvement on chest CT scans than in those with no lung involvement on chest CT scans. A comparison of lung involvement levels revealed no difference was found between the groups. The MMP-9/TIMP-1 ratio was 5.8 in the group with lung involvement on chest CT scans and 6.1 in the group without lung involvement on chest CT scans. No difference was found between the two groups. A comparison with respect to lung involvement levels showed that the MMP-9/TIMP-1 ratio difference was found between the groups. Conclusion: Diagnostic and treatment methods targeting MMP-9 activity or neutrophil activation may be important in predict-ing lung involvement in COVID-19 and directing clinical outcomes.
Yazarlar (10)
1
Nazlım Aktuğ Demir
2
Sema Yilmaz Kirik
3
Şua Sümer
4
Onur Ural
5
Hatice Esranur Kiratlı
6
Hüsamettin Vatansev
7
Esra Paydas Hayatsal
8
Ugur Arslan
9
Hakan Cebeci
10
Lütfi Saltuk Demir
Anahtar Kelimeler
COVID-19
MMP-9
TIMP-1
Kurumlar
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Tip Fakültesi
Konya Turkey
Metrikler
4
Atıf
10
Yazar
3
Anahtar Kelime