Scopus
YÖKSİS Eşleşti
Diagnostic efficacy of diffusion-weighted MRI for pre-operative assessment of myometrial and cervical invasion and pelvic lymph node metastasis in endometrial carcinoma
Journal of Medical Imaging and Radiation Oncology · Ekim 2014
YÖKSİS Kayıtları
Diagnostic efficacy of diffusion weighted MRI for pre operative assessment of myometrial and cervical invasion and pelvic lymph node metastasis in endometrial carcinoma
Journal of Medical Imaging and Radiation Oncology · 2014 SCI-Expanded 3 atıf
PROFESÖR ÇETİN ÇELİK →
Diagnostic efficacy of diffusion weighted MRI for pre operative assessment of myometrial and cervical invasion and pelvic lymph node metastasis in endometrial carcinoma
Journal of Medical Imaging and Radiation Oncology · 2014 SCI-Expanded 3 atıf
PROFESÖR ALAADDİN NAYMAN →
Diagnostic efficacy of diffusion weighted MRI for pre operative assessment of myometrial and cervical invasion and pelvic lymph node metastasis in endometrial carcinoma
Journal of Medical Imaging and Radiation Oncology · 2014 SCI-Expanded 1 atıf
PROFESÖR MUSTAFA KOPLAY →
Diagnostic efficacy of diffusion weighted MRI for pre operative assessment of myometrial and cervical invasion and pelvic lymph node metastasis in endometrial carcinoma
Journal of Medical Imaging and Radiation Oncology · 2014 SCI-Expanded 1 atıf
PROFESÖR ÇETİN ÇELİK →
Diagnostic efficacy of diffusion weighted MRI for pre operative assessment of myometrial and cervical invasion and pelvic lymph node metastasis in endometrial carcinoma
Journal of Medical Imaging and Radiation Oncology · 2014 SCI-Expanded 1 atıf
PROFESÖR ÇETİN ÇELİK →
Diagnostic efficacy of diffusion weighted MRI for pre operative assessment of myometrial and cervical invasion and pelvic lymph node metastasis in endometrial carcinoma
Journal of Medical Imaging and Radiation Oncology · 2014 SCI-Expanded 1 atıf
PROFESÖR MUSTAFA KOPLAY →
Diagnostic efficacy of diffusion-weighted MRI for pre-operative assessment of myometrial and cervical invasion and pelvic lymph node metastasis in endometrial carcinoma
Journal of Medical Imaging and Radiation Oncology · 2014 SCI-Expanded
PROFESÖR ÇETİN ÇELİK →
Diagnostic efficacy of diffusion weighted MRI for pre operative assessment of myometrial and cervical invasion and pelvic lymph node metastasis in endometrial carcinoma
Journal of Medical Imaging and Radiation Oncology · 2014 SCI-Expanded
PROFESÖR ÇETİN ÇELİK →
Diagnostic efficacy of diffusion weighted MRI for pre operative assessment of myometrial and cervical invasion and pelvic lymph node metastasis in endometrial carcinoma
Journal of Medical Imaging and Radiation Oncology · 2014 SCI-Expanded
PROFESÖR MUSTAFA KOPLAY →
Makale Bilgileri
DergiJournal of Medical Imaging and Radiation Oncology
Yayın TarihiEkim 2014
Cilt / Sayfa58 · 538-546
Scopus ID2-s2.0-84907922477
Özet
Introduction: To determine the diagnostic accuracy of diffusion-weighted magnetic resonance imaging (DW-MRI) for the pre-operative assessment of patients with endometrial carcinoma and to assess myometrial and cervical invasion as well as pelvic lymph node metastasis. Methods: Fifty-eight women who underwent surgery for histopathologically confirmed endometrial carcinoma were included in the current study. Prior to surgery, patients were evaluated using pelvic DW-MRI and gadolinium-enhanced T1-weighted imaging (Gd-T1WI). Gd-T1WI was evaluated together with T2-weighted images. DW-MR images were obtained in the axial plane using echo-planar spin-echo pulse sequences with different b factors. Endometrial carcinomas were observed as areas of increased intensity on DW-MRI images, and their intensity was compared with the surrounding hypo-intense myometrium. Pre-operative DW-MRI and Gd-T1WI results were compared with post-operative histopathological findings that served as reference standards. Results: The sensitivity, specificity, positive (PPV) and negative predictive values (NPV), and diagnostic accuracy of DW-MRI for differentiation between superficial myometrial invasion and deep myometrial invasion were 85%, 89%, 81%, 92% and 88%, respectively. The sensitivity, specificity and diagnostic accuracy rates were 82%, 91% and 89.6% for cervical invasion and 100%, 96% and 96.5% for pelvic lymph node metastasis, respectively. The sensitivity, specificity, PPV and NPV, and diagnostic accuracy of Gd-T1WI for differentiation between superficial myometrial invasion and deep myometrial invasion were 85%, 81.5%, 71%, 91% and 83%, respectively. The sensitivity, specificity and diagnostic accuracy were 73%, 89% and 86% for cervical invasion, respectively. Conclusions: These findings suggest that DW-MRI may be a good diagnostic tool with high sensitivity and specificity for assessing myometrial invasion and detecting tumour extension. We suggest that DW-MRI should be considered as a routine part of the pre-operative pelvic MRI in all patients with endometrial carcinoma.
Yazarlar (9)
1
M. Koplay
ORCID: 0000-0001-7513-4968
2
N. U. Doğan
3
Hasan Erdogan
4
Mesut Sivri
5
Cengiz Erol
6
Alaaddin Nayman
7
Pınar Karabağlı
ORCID: 0000-0002-5558-0175
8
Y. Paksoy
9
Çetin Çelik
ORCID: 0000-0001-6165-5092
Anahtar Kelimeler
Diffusion-weighted imaging
Endometrial carcinoma
MRI
Staging
Kurumlar
İstanbul Medipol Üniversitesi
Istanbul Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
31
Atıf
9
Yazar
4
Anahtar Kelime