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Evaluation of biocompability of supramolecular calixarene on L-929 by real time cell analysis

Proceedings of the 2017 IEEE 7th International Conference on Nanomaterials: Applications and Properties, NAP 2017 · Aralık 2017

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YÖKSİS Kayıtları
Evaluation of Biocompability of Supramolecular Calixarene on L-929 by Real Time Cell Analysis
Institute of Electrical and Electronics Engineers Xplore · 2017 Scopus
PROFESÖR ŞEREF ERTUL →
Evaluation of Biocompability of Supramolecular Calixarene on L-929 by Real Time Cell Analysis
Institute of Electrical and Electronics Engineers Xplore · 2017 Scopus
DOKTOR ÖĞRETİM ÜYESİ PEMBEGÜL UYAR ARPACI →
Evaluation of Biocompability of Supramolecular Calixarene on L-929 by Real Time Cell Analysis
Institute of Electrical and Electronics Engineers Xplore · 2017 Scopus
ÖĞRETİM GÖREVLİSİ FATİH ÖZCAN →

Makale Bilgileri

DergiProceedings of the 2017 IEEE 7th International Conference on Nanomaterials: Applications and Properties, NAP 2017
Yayın TarihiAralık 2017
Cilt / Sayfa2017-January
DOI10.1109/NAP.2017.8190339
Scopus ID2-s2.0-85046272156
Özet The cytotoxicity test is one of the biological evaluation and screening tests that use tissue cells in vitro to observe the cell growth, reproduction and morphological effects by medical devices. Cytotoxicity is preferred as a pilot project test and an important indicator for toxicity evaluation of medical devices as it is simple, fast, has a high sensitivity and can save animals from toxicity. Three types of cytotoxicity test are stated in the International Organization for Standardization 109993-5: Extract, direct contact and indirect contact tests. The xCELLigence real-time cell analysis system shows a significant potential in regards to cytotoxicity in recent years. The proliferation of L-929 were observed in the Real-Time Cell Analysis (RTCA) Systems. Our research directs that calixarene shows no cytotoxicity at a concentration range of 25 to 100 μg/mL on L929 cells. There were no significant differences between the L929 cell indexes of the control and all testing groups at 24, 48 and 72 h.

Yazarlar (5)

1
Pembegul Uyar Arpaci
2
Fatih Ozcan
3
N. Omar
4
F. Ozcan
5
Seref Ertul

Anahtar Kelimeler

Biocompatibility Calixarene Cytotoxicity xCELLigence

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

2
Atıf
5
Yazar
4
Anahtar Kelime

Sistemimizdeki Yazarlar

ŞE
ŞEREF ERTUL
PROFESÖR

Hızlı Erişim

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