Scopus
YÖKSİS Eşleşti
Oxygen transmission rates of skin substitutes and graft survival
Burns · Kasım 2023
YÖKSİS Kayıtları
Oxygen transmission rates of skin substitutes and graft survival
BURNS · 2023 SCI-Expanded
ÖĞRETİM GÖREVLİSİ FATİH ÖZCAN →
Makale Bilgileri
DergiBurns
Yayın TarihiKasım 2023
Cilt / Sayfa49 · 1654-1662
Scopus ID2-s2.0-85161004614
Özet
Aim: Oxygen is required for cell migration into the scaffold and for the survival of the overlying graft in the use of a single-layer scaffold. In the absence of diffusion from the avascular wound base, such as in areas above the bone/tendon, oxygen delivery from the lateral edges of the scaffold is important. This study compared the oxygen permeability of skin scaffolds, currently commercially available in Turkey (Nevelia®, MatriDerm®, and Pelnac®), in the lateral plane. Materials and methods: To measure oxygen permeability, an interconnected closed system was created. Oxygen permeability was evaluated based on the color change that occurred as a result of the reaction of iron with oxygen. After the dermal matrices placed in the closed system were exposed to oxygen, the color change on the surface of the dermal matrices was measured, and electron microscopic images were recorded to compare deformation before and after the procedure. Results: Two scaffolds did not show deformation after the procedure while Pelnac® had minimal deformation. The oxygen rates on the nitrogen side of the test apparatus were found to be 29%, 34%, and 27% for Nevelia®, MatriDerm®, and Pelnac®, respectively; and the oxygen transmission lengths (length of color change) of these scaffolds in the lateral plane were 1, 2, and 0.5 cm, respectively. Conclusion: Although none of the scaffolds showed significant deformation, and all continued to exhibit their scaffold properties after the procedure, MatriDerm® was determined to be the most suitable scaffold for use in avascular areas, with a 2-cm oxygen transmission length in terms of lateral oxygenation.
Yazarlar (7)
1
Ahmet Çınar YASTI
2
Bayram Çolak
3
Fatih Ozcan
4
Kemal Kısmet
5
Aziz Ahmet SÜREL
6
Ali Emre Akgün
7
Merve AKIN
ORCID: 0000-0001-7224-4774
Anahtar Kelimeler
Burns
Chronic wound
Grafting
Oxygen transmission
Scaffold
Kurumlar
Ankara City Hospital
Ankara Turkey
Health Sciences University Medical School
Derince Turkey
Selçuk Üniversitesi
Selçuklu Turkey
University of Health Sciences
Istanbul Turkey