Scopus
YÖKSİS ISSN Eşleşti
SJR Q2
Lacrimal function and ocular complications in patients treated with systemic isotretinoin
European Journal of Ophthalmology · Ocak 2002
YÖKSİS Kayıtları — ISSN Eşleşmesi
Serum vitamin D deficiency and its association with systemic disease in exfoliation syndrome
2013 ISSN: 1120-6721 SCI
Prof. Dr. BANU BOZKURT →
Comparison of cytotoxic, apoptotic and oxidative properties of Akacid plus and chlorhexidine in corneal epithelial cell culture
2023 ISSN: 1120-6721 SCI
Prof. Dr. SERDAR KARAKURT →
In vivo laser confocal microscopic findings in patients with epithelial basement membrane dystrophy
2009 ISSN: 1120-6721 SCI-Expanded
Prof. Dr. BANU BOZKURT →
Serum allergen specific immunoglobulin E levelsin patients with allergic conjunctivitis
2008 ISSN: 1120-6721 SCI-Expanded
Prof. Dr. BANU BOZKURT →
Systemic associations and prevalence of exfoliation syndrome in patients scheduled for cataract surgery
2008 ISSN: 1120-6721 SCI-Expanded
Prof. Dr. BANU BOZKURT →
Lacrimal function and ocular complications in patients treated with systemic isotretinoin
2002 ISSN: 1120-6721 SCI-Expanded
Prof. Dr. BANU BOZKURT →
Makale Bilgileri
ISSN11206721
Yayın TarihiOcak 2002
Cilt / Sayfa12 · 173-176
Scopus ID2-s2.0-0035987022
Özet
Purpose. To evaluate the effect on lacrimal function and ocular complications in patients with severe acne vulgaris during systemic treatment with 13-cis-retinoic acid (isotretinoin). Methods. Forty patients with acne vulgaris were treated with systemic isotretinoin at dosages of 0.5-1 mg/kg per day for two months. Full ophthalmologic examination, Schirmer I test, fluorescein break-up (BUT) and microbiological investigations of the conjunctival flora were done before, during the second month and at least one month after the end of the treatment. Results. The average Schirmer values before and after the treatment were 21.6 mm/5 minutes (SD ± 7.01) and 18.48 mm/5 minutes (SD ± 7.87) respectively. After the treatment BUT was less than 10 seconds in 50% of the patients and 55% had blepharitis. Subjective symptoms like dryness, itching and contact lens intolerance occurred in 42.5% and colonization of the conjunctiva by Staphylococcus aureus increased significantly during treatment (p = 0.031). All abnormal findings disappeared one month after the cessation of treatment. Discussion. Isotretinoin causes signs and symptoms of dry eye, probably by reducing meibomian gland function, but ocular complications are generally not serious when low doses are used for a limited time, and are reversible after discontinuation.
Yazarlar (5)
1
Banu Bozkurt
ORCID: 0000-0002-9847-3521
2
M. İrkeç
3
Nilgun Atakan
4
Mehmet Orhan
5
P. Ö Geyik
Anahtar Kelimeler
Acne vulgaris
Isotretinoin
Lacrimal function
Ocular complications
Kurumlar
Hacettepe Üniversitesi
Ankara Turkey
Scimago Dergi (ISSN Eşleşmesi)
European Journal of Ophthalmology
Q2
SJR Skoru0,647
H-Index69
YayıncıWichtig Publishing Srl
ÜlkeItaly
Medicine (miscellaneous) (Q2)
Ophthalmology (Q2)
Metrikler
60
Atıf
5
Yazar
4
Anahtar Kelime