Scopus
YÖKSİS DOI Eşleşti
SJR Q2
In vivo confocal microscopic evaluation of the inflammatory response in non-epithelial herpes simplex keratitis
Current Eye Research · Aralık 2012
YÖKSİS Kayıtları
In Vivo Confocal Microscopic Evaluation of the Inflammatory Response in Non epithelial Herpes Simplex Keratitis
CURRENT EYE RESEARCH · 2012 SCI-Expanded
Prof. Dr. BANU BOZKURT →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Characterization of T Lymphocyte subtypes in endotoxin induced uveitis and effect of pentoxifylline treatment
2002 ISSN: 0271-3683 SCI-Expanded 7 atıf
Prof. Dr. ABDULKERİM KASIM BALTACI →
Association of Apolipoprotein E Polymorphism with Intravitreal Ranibizumab Treatment Outcomes in Age-Related Macular Degeneration
2015 ISSN: 0271-3683 SCI-Expanded
Prof. Dr. ŞABAN GÖNÜL →
Association of Apolipoprotein E Polymorphism with Intravitreal Ranibizumab Treatment Outcomes in Age-Related Macular Degeneration
2016 ISSN: 0271-3683 SCI-Expanded
Prof. Dr. NESLİHAN İYİT →
Association of Apolipoprotein E Polymorphism with Intravitreal Ranibizumab Treatment Outcomes in Age-Related Macular Degeneration
2015 ISSN: 0271-3683 SCI-Expanded
Prof. Dr. ŞABAN GÖNÜL →
Novel Zinc Finger Protein Gene 469 (ZNF469) Variants in Advanced Keratoconus
2017 ISSN: 0271-3683 SCI-Expanded Q3
Dr. Öğr. Üyesi ÖZKAN BAĞCI →
In Vivo Confocal Microscopic Evaluation of the Inflammatory Response in Non epithelial Herpes Simplex Keratitis
2012 ISSN: 0271-3683 SCI-Expanded
Prof. Dr. BANU BOZKURT →
Retinal Vascular Changes in Acne Patients Under Isotretinoin Treatment: An Optical Coherence Tomography Angiography Study
2026 ISSN: 0271-3683 SCI-Expanded Q2
Öğr. Gör. SERHAT EKER →
Retinal Vascular Changes in Acne Patients Under Isotretinoin Treatment: An Optical Coherence Tomography Angiography Study
2025 ISSN: 0271-3683 SCI-Expanded Q2
Doç. Dr. FATMA TUNÇEZ AKYÜREK →
Makale Bilgileri
Dergi
Current Eye Research
ISSN02713683
Yayın TarihiAralık 2012
Cilt / Sayfa37 · 1099-1106
Scopus ID2-s2.0-84870280786
Özet
Purpose: To investigate the characteristics of the inflammatory response detected in corneas with active non-epithelial herpes simplex virus (HSV) keratitis. Materials and methods: The study was designed as a cross-sectional study undertaken at a university setting. Twenty-one eyes of 21 patients with a mean age of 40.1±13.0 years (range: 18-70 years) and whose corneal findings were compatible with active HSV keratitis were included. All patients were evaluated with in vivo confocal microscopy (Confoscan 3, Nidek). Fifty healthy, age-matched subjects served as controls. The features and extent of corneal inflammation, degree of involvement of subbasal nerve plexus and endothelial cell density were evaluated. Results: Seven eyes (33.3%) demonstrated stromal keratitis, six (28.6%) endotheliitis and eight (38.1%) presented with keratouveitis. Intraepithelial inflammatory cell infiltration, consisting of dendritic and small round cells, was observed in 11 eyes (52.4%). Stromal involvement was detected in 95.2% of eyes in the form of focal and diffuse cellular infiltrates; of these, anterior, posterior and pan stromal infiltration was observed in 85.7, 71.4 and 47.6% of cases, respectively. No particular keratic precipitate morphology was found to be diagnostic for HSV keratitis. The mean endothelial cell density of eyes with HSV keratitis (2437±599 cells/mm2) was significantly lower (-18.8%) than that of controls (3003±250 cells/mm2); (p < 0.001). The mean subbasal nerve density of patients with HSV keratitis (474.5±227.8 μm/frame) was significantly lower than that of controls (1589.6±499.0 μm/frame) (p < 0.001). Conclusions: Non-epithelial HSV keratitis related inflammatory response is characterized by cellular infiltration of all corneal layers, attenuation of the subbasal nerve plexus and endothelial cell loss. © 2012 Informa Healthcare USA, Inc.
Yazarlar (6)
1
Mehmet Cem Mocan
2
M. İrkeç
3
Dimitrios G. Mikropoulos
4
Banu Bozkurt
ORCID: 0000-0002-9847-3521
5
Mehmet Orhan
6
Anastasios G. Konstas
Anahtar Kelimeler
Herpetic keratitis
Inflammation
In vivo confocal microscopy
Kurumlar
Hacettepe Üniversitesi
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey
University General Hospital of Thessaloniki "AHEPA"
Thessaloniki Greece
Scimago Dergi (ISSN Eşleşmesi)
Current Eye Research
Q2
SJR Skoru0,685
H-Index98
YayıncıTaylor and Francis Ltd.
ÜlkeUnited Kingdom
Ophthalmology (Q2)
Sensory Systems (Q2)
Cellular and Molecular Neuroscience (Q3)
Metrikler
37
Atıf
6
Yazar
3
Anahtar Kelime