Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Correlation of corneal endothelial cell density with corneal tomographic parameters in eyes with keratoconus
Turkish Journal of Ophthalmology · Ekim 2017
YÖKSİS Kayıtları
Correlation of Corneal Endothelial Cell Density with Corneal Tomographic Parameters in Eyes with Keratoconus
Türk Oftalmoloji Dergisi · 2017 TR DİZİN
PROFESÖR BANU BOZKURT →
Correlation of Corneal Endothelial Cell Density with Corneal Tomographic Parameters in Eyes with Keratoconus
Türk Oftalmoloji Dergisi · 2017 TR DİZİN
PROFESÖR SÜLEYMAN OKUDAN →
Makale Bilgileri
DergiTurkish Journal of Ophthalmology
Yayın TarihiEkim 2017
Cilt / Sayfa47 · 255-260
Scopus ID2-s2.0-85033782991
Erişim🔓 Açık Erişim
Özet
Objectives: To examine changes in corneal endothelial cell density (ECD) in different stages of keratoconus and evaluate its correlation with corneal tomographic parameters. Materials and Methods: Two hundred six patients with keratoconus were enrolled in the study. Corneal topography was performed by Sirius (CSO, Italy), which has a rotating Scheimpflug camera and a Placido disc topographer. Automatic endothelial analysis was done with the non-contact endothelial microscope (20x probe) of Confoscan-4 (NIDEK, Japan). The eyes were classified into stages based on steepest keratometric value as follows: mild <45 D; moderate 45-52 D; severe >52 D and according to thinnest cornea thickness (TCT) as <400 μm, 400-450 μm, and >450 μm. Tomographic and endothelial cell parameters were compared among the groups using Kruskal-Wallis test and the correlations between them were analyzed using Spearman correlation. Results: The study included 391 eyes of 100 male (24.29±7.7 years, range 11-47 years) and 106 female (26.26±7.5 years, range 13-45 years) patients (p=0.07). Mean ECD values were 2628±262 cells/mm2, 2541.9±260.4 cells/mm2, and 2414.6±384.3 cells/mm2 in mild, moderate, and severe keratoconus, respectively (p<0.001) and 2592.3±277 cells/mm2, 2502±307 cells/mm2 and 2348±296 cells/mm2 in corneas with TCT values >450 μm, 400-450 μm, and <400 μm, respectively (p<0.001). ECD showed significant negative correlation with keratometric and elevation parameters and positive correlation with pachymetric parameters (p<0.05). Conclusion: As endothelial cell numbers seem to decrease with the progression of keratoconus, specular/confocal microscopy screening should be carried out, especially in eyes with advanced stages and corneas with TCT <400 μm.
Yazarlar (6)
1
Banu Bozkurt
ORCID: 0000-0002-9847-3521
2
Mevlut Yilmaz
3
Ali Mesen
4
U. Kamis
5
Bengu Ekinci Koktekir
6
Süleyman Okudan
Anahtar Kelimeler
Cornea endothelial cell density
Corneal tomography
Keratoconus
Morphological changes
Specular microscopy
Kurumlar
Dr M�nif Islamoğlu State Hospital
Kastamonu Turkey
Konya Dünya Göz Hospital
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
5
Atıf
6
Yazar
5
Anahtar Kelime