Scopus
YÖKSİS Eşleşti
A new look at the safety and tolerability of prostaglandin analogue eyedrops in glaucoma and ocular hypertension
Expert Opinion on Drug Safety · Ocak 2022
YÖKSİS Kayıtları
A new look at the safety and tolerability of prostaglandin analogue eyedrops in glaucoma and ocular hypertension
Expert Opinion on Drug Safety · 2022 SCI-Expanded
PROFESÖR BANU BOZKURT →
Makale Bilgileri
DergiExpert Opinion on Drug Safety
Yayın TarihiOcak 2022
Cilt / Sayfa21 · 525-539
Scopus ID2-s2.0-85118377882
Özet
Introduction: In the last 25 years, topical prostaglandin analogues (PGAs) have emerged to become first line and first choice therapeutic options in the management of glaucoma and ocular hypertension (OHT). Although the short-term efficacy and safety of PGAs has been extensively investigated, less is known about their long term safety and tolerability. This gap in current knowledge is clinically relevant, because treatment-related adverse events and long-term tolerability issues are key determinants of the overall success of long-term therapy and the final outcome of a lifelong, symptomless disease like glaucoma. Areas covered: We include selected evidence pertaining to the safety and tolerability of available and emerging PGA formulations. We also outline PGA formulations with different concentrations of the active ingredient, different preservatives, and preservative-free (PF) options. Expert opinion: Undoubtedly PGAs will continue to play a major role in the medical therapy of glaucoma and OHT. Despite extensive literature and prolonged clinical experience with these agents worldwide, a number of areas that warrant further research have been identified in the present review. Recently launched novel PGAs, or those still in development offer new opportunities and future challenges.
Yazarlar (9)
1
Andreas Katsanos
ORCID: 0000-0001-6623-8503
2
Ivano Riva
3
Banu Bozkurt
ORCID: 0000-0002-9847-3521
4
Gábor Holló
ORCID: 0000-0002-0904-4849
5
Luciano Quaranta
6
Francesco Oddone
7
M. İrkeç
8
Gordon N. Dutton
9
Anastasios G. Konstas
Anahtar Kelimeler
adverse events
bimatoprost
Glaucoma medical therapy
latanoprost
oht
prostaglandins
safety
tafluprost
tolerability
travoprost
Kurumlar
Aristotle University of Thessaloniki
Thessaloniki Greece
Glasgow Caledonian University
Glasgow United Kingdom
Hacettepe Üniversitesi
Ankara Turkey
Istituto Clinico Sant'Anna
Brescia Italy
Prima Medica Health Centers
Budapest Hungary
Selçuk Üniversitesi
Selçuklu Turkey
Tutkimusz Ltd
Solymar Hungary
Università degli Studi di Pavia
Pavia Italy
University of Ioannina
Ioannina Greece
Metrikler
9
Atıf
9
Yazar
10
Anahtar Kelime