Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q3
Mannose-binding lectin (MBL) levels in children with Hashimoto’s thyroiditis
Northern Clinics of Istanbul · Ocak 2023
YÖKSİS Kayıtları
Mannose-Binding Lectin (MBL) Levels in Children with Hashimoto\u2019s Thyroiditis
Northern Clinics of Istanbul · 2023 ESCI
Prof. Dr. RESUL YILMAZ →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Comparison of \u201cBurden of Disease\u201d in Elderly and Non-elderly Patients with Prediabetes: A Cross-sectional Study
2021 ISSN: 2148-4902 TR DİZİN
Doç. Dr. KEMAL EROL →
Dermoscopic rainbow pattern: A strong clue to malignancy or just a light show?
2020 ISSN: 2148-4902 Emerging Sources Citation Index, Turkish Medical Index of the Turkish Academic Network and Information Center (ULAKBIM)
Doç. Dr. MURAT ÇELİK →
Mannose-Binding Lectin (MBL) Levels in Children with Hashimoto\u2019s Thyroiditis
2023 ISSN: 2148-4902 ESCI
Prof. Dr. RESUL YILMAZ →
Effects of Early Physical Therapy on Motor Development in Children with Down Syndrome
2022 ISSN: 2148-4902 TR DİZİN
Dr. Öğr. Üyesi MEHMET AKİF BÜYÜKAVCI →
New threat: 2019 Novel Coronavirus Infection and Infection Control Perspective in Turkey
2020 ISSN: 2148-4902 TR DİZİN
Prof. Dr. FATİH KARA →
The clinical and immunological characteristics of common variable immunodeficiency in adults and older adults
2024 ISSN: 2148-4902 ESCI
Doç. Dr. ERAY YILDIZ →
Assessment of serum vascular endothelial growth factor, nitric oxide and asymmetric dimethyl arginine levels in non-small cell lung cancer
2025 ISSN: 2148-4902 SCI-Expanded Q3
Prof. Dr. ALİ ÜNLÜ →
Comparative analysis of single-dose platelet-rich plasma and hyaluronic acid therapies in knee osteoarthritis: A 12-week follow-up study
2025 ISSN: 2148-4902 TR DİZİN
Dr. Öğr. Üyesi EZGİ AKYILDIZ TEZCAN →
Makale Bilgileri
ISSN21484902
Yayın TarihiOcak 2023
Cilt / Sayfa10 · 353-358
Scopus ID2-s2.0-85164739330
Erişim🔓 Açık Erişim
Özet
OBJECTIVE: Hashimoto’s thyroiditis (HT) was described many years ago, but the etiopathogenesis remains unclear. Man-nose-binding lectin (MBL) initiates complement activation in the lectin pathway. We determined MBL levels in children with HT and the associations thereof with thyroid hormone and thyroid autoantibody levels. METHODS: Thirty-nine patients with HT and 41 controls were enrolled from the pediatric outpatient clinics. Subjects were grouped according to their thyroid functions: Euthyroid, marked hypothyroidism and clinical/subclinical hyperthyroidism. MBL levels were compared among these groups. Serum MBL levels of the subjects were determined using MBL Human ELISA kit. RESULTS: Serum MBL levels were studied in serum samples from the 80 subjects (48 (60.0%) females). MBL levels in HT and control groups were 50.787±34.718 and 50.593±44.28 ng/ml (p=0,983), respectively. In HT group, there was no significant difference in MBL levels between thyroid function groups (p=0.869). In addition, gender was not detected as a factor for serum MBL levels. Also we found negative correlation between WBC and serum MBL levels (r=-0.532; p=0.050). Otherwise there was no correlation between TSH, anti-TPO and anti-TG with serum MBL levels. CONCLUSION: MBL levels did not decrease in HT patients. Further research is needed to elucidate more fully any role for MBL in the development of autoimmune thyroid disease.
Yazarlar (4)
1
Ali Gul
2
Nihal Hatipoglu
3
Resul Yilmaz
4
Haci Omer Ates
Anahtar Kelimeler
Autoimmune disease and hypothyroidism
children
Hashimoto’s thyroiditis
mannose binding lectin
Kurumlar
Erciyes University, Faculty of Medicine
Kayseri Turkey
Selçuk Tip Fakültesi
Konya Turkey
Tokat Gaziosmanpaşa Üniversitesi
Tokat Turkey
Scimago Dergi (ISSN Eşleşmesi)
Northern Clinics of Istanbul
Q3
OA
SJR Skoru0,322
H-Index9
YayıncıKare Publishing
ÜlkeTurkey
Medicine (miscellaneous) (Q3)
Metrikler
1
Atıf
4
Yazar
4
Anahtar Kelime